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OpenTrials
Completed

NCT Number: NCT03557528

Role of Low Inferior Mesenteric Artery Ligation During Laparoscopic Surgery for Rectosigmoid Cancer

During sigmoid or rectal cancer surgery, dissection of lymphnodes at the origin of inferior mesenteric artery is mandatory. Nevertheless, ligation of the origin of IMA should compromise blood supply to left colon and affect anastomosis. The aim of this retrospective evaluation is to compare high and low IMA ligation with preservation of LCA, with or without skeletonization of the origin of IMA in laparoscopic colorectal resection.

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Key information

Conditions

Rectosigmoid Adenocarcinoma

Sex eligibility

All sexes

Study type

Observational

Primary location

Policlinico Umberto I

Roma, 00161, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • stage I-III carcinoma

Exclusion criteria

  • stage IV
  • Urgent resection
  • conversion to open surgery

Treatment and study plan

laparoscopic colorectal resection

Procedure

Gruop 1: laparoscopic rectosigmoid resection with standard ligation of mesenteric artery at its origin Group 2: Laparoscopic rectosigmoid resection with low ligation of inferior mesenteric artery and its skeletonization with en bloc removal of all lymph nodes

Primary outcomes

  1. effectivenes of lymphnode dissection

    Time frame: 3 years

    number of dissected lymphnodes

Secondary outcomes

  1. complication

    Time frame: 3 years

    incidence of anasthomotic leaks

Sponsors and collaborators

Lead sponsor

University of Roma La Sapienza

Other

Registry information

Official study title

Evaluation of the Role of Low Inferior Mesenteric Artery Ligation During Laparoscopic Surgery for Rectosigmoid Tumors

Important dates

Study start
2014
Primary completion
2016
Study completion
2017
First posted
Jun 15, 2018
Registry last updated
Jun 15, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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