Role of Inferior Colliculi in Auditory Hallucinations

Inclusion criteria

• The patient must have given their free and informed consent and signed the consent form
• The patient must be a member or beneficiary of a health insurance plan
• DSM-5 diagnosis of schizophrenic disorder (based on clinical assessment and confirmed by the MINI 7.0 interview)
• Patient with a schizophrenic disorder lasting ≤ 20 years
• Patient treated in a psychiatric unit as an inpatient (in non-specialized care) or outpatient or under a mandatory ambulatory psychiatric care programme
• Clinical condition compatible with imaging based on clinical judgment
• Ability to understand, write, and read French

Specific inclusion criteria for the group (SCZ+/HA+) • Patient with a PANSS score (question P3 regarding hallucinations) ≥ 4 (corresponds to PANSS (P3) 4, 5, 6, and 7 patients) AND having experienced hallucinations in the past 15 days.

Specific inclusion criteria for the control group

• Patient with a PANSS score (question P3 regarding hallucinations) = 1) AND having not experienced any hallucinations in the past 15 days.

Exclusion criteria

• The patient is under safeguard of justice or state guardianship
• Contraindications to magnetic resonance imaging, including severe claustrophobia, based on clinical judgment.
• Congenital or acquired deafness
• Suicide risk, based on clinical judgment
• Patient with moderate to severe intellectual disability, based on medical records
• Patient with moderate to severe neurocognitive disorders, based on medical records
• Patient receiving anticholinergic therapy (biperiden-Akineton, trihexyphenidyl-Artane, tropatepine-Lepticur)
• Patient participating in an interventional study involving a drug or medical device, or a Category 1 RIPH within 3 months prior to inclusion
• Person under judicial protection
• Pregnant, parturient, or breastfeeding woman
• Person unable to express consent