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NCT Number: NCT06711263

Role of Herbal Based Mouthwashes in Plaque Control

Herbal medicine has been used for thousands of years. Traditional herbal medicine is used by an estimated 80% of the world's population for primary health care. Herbal treatments have gained popularity as a dietary supplement for illness prevention and as an alternative/complementary therapy in recent years. Herbal remedies come in a wide variety of forms and can be found on the market all over the world.

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Key information

About this study

Herbal mouthwashes have been increasingly popular over time. Ethnomedicines are the term used to describe them. Various substances have been tested, with phytopharmacological analyses yielding contradictory results. Many previous studies had tested the antiplaque efficiency of one herbal mouthwash with contradicting results, other studies have tested the Antiplaque efficiency of chlorhexidine, tea tree oil and Miswak, some studies had given positive outcomes and benefits of Miswak on the gingiva and others when comparing between the efficacy of Miswak over chlorhexidine mouth wash in dental practice provided results favouring both these mouthwashes.

In our proposed study we will compare the antiplaque efficiency of three herbal kinds of mouthwash, Miswak, tea tree oil and Resveratrol mouthwash. Plaque and gingival bleeding scores will be taken before the study from 6 different teeth and retaken after 2 weeks and four weeks respectively the use of the mouthwash. This study is single-blinded. Antiplaque and gingival bleeding scores from the three mouthwashes will be recorded over a period of a month and statistical analysis will be performed

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who are medically fit
  • Patients with gingival inflammation not progressed into periodontitis (AAP classification
  • Patients between the age of 18-60 years

Exclusion criteria

  • Patients who are medically compromised
  • Patient who have undergone a periodontal therapy for the past 3 months
  • Patients who are healthy but have been using herbal mouthwashes

Treatment and study plan

Mouthwash Product

Other
  • In the Initial Visit-Baseline, and subsequent visits, participants will be called in the morning. Morning hours will be chosen for examination, as it will reduce the risk of bias and also help in quantifying results. plaque and gingival scores will be recorded and the First herbal mouthwashes will be given, participants will also be provided new tooth-brushes (Oral B-soft).
  • They will be asked to follow their routine oral hygiene habits. They will be asked to come back after 2 weeks for plaque and gingival bleeding scores recording for the second visit and again after 2weeks post the second visit for the third and final visit to record their plaque and gingival bleeding scores.

Other names: chlorhexidine, resverotriol, miswak, tea tree oil

Primary outcomes

  1. plaque score

    Time frame: From Baseline-pre-intervention to the end of treatment at 4 weeks

    To assess the plaque score

Secondary outcomes

  1. gingival bleeding score

    Time frame: from pre-intervention to the end of the treatment at 4 weeks

    To assess gingival bledding score

Study contacts

Contact information is provided by the study sponsor or research team.

sudhir Rama Varma, MDS

CONTACT

[email protected]

971506595075

Sponsors and collaborators

Lead sponsor

Ajman University

Other

Registry information

Official study title

Role of Herbal Based Mouthwashes in Plaque Control. a Randomized Clinical Control Trial

Acronym: mouthwash

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Dec 2, 2024
Registry last updated
Dec 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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