Active, Not Recruiting

NCT Number: NCT07080372

Role of Early API in Accurately Differentiating Hepatocellular Carcinoma From Dysplastic Nodules in Cirrhotic Patients

Liver cirrhosis is a common consequence of chronic liver disease, resulting from sustained hepatic injury due to various etiologies. Cirrhosis predisposes individuals to the development of hepatocellular carcinoma (HCC), the most prevalent primary malignancy of the liver. Among cirrhotic patients, distinguishing between hepatocellular carcinoma and dysplastic nodules is crucial for timely diagnosis, treatment planning, and prognostic assessment.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Dysplastic Nodule

Age range

5 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Lahore General Hospital

Lahore, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with abnormal LFTs
Liver lesions of various sizes
Patients with chronic liver disease
Individuals undergoing routine liver screening
Willing participants who consent to the study

Exclusion criteria

Children less than 5years
Patients who are allergic or have a history of allergy to contrast media
Patients with deranged renal function tests
Pregnant women

Treatment and study plan

assesment

Diagnostic Test

This study aims to assess the role of early arterial phase in detecting and differentiating hepatocellular carcinoma from dysplastic nodules in chronic liver disease patients.

Primary outcomes

self administered proforma form

Time frame: 12 Months

A clinical history form is a structured document used to gather comprehensive information about a patient's medical background and current health status. It typically includes sections for identifying patient demographics, past medical history, family history, social history, medications, allergies, and a detailed account of the current illness or complaint.

Sponsors and collaborators

Lead sponsor

Superior University

Other

Registry information

Official study title

Role of Early Arterial Phase Imaging in Accurately Differentiating Hepatocellular Carcinoma From Dysplastic Nodules in Cirrhotic Patients

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2026
First posted: Jul 23, 2025
Registry last updated: Jul 23, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.