Role of Cervical Fascia Flap in Decreasing the Incidence of Pharyngocutaneous Fistula After Total Laryngectomy

This study was conducted to evaluate the potential role of using the cervical fascia flap over the pharyngeal closure line to enhance healing and subsequently to decrease the incidence of pharyngocutaneous fistula after total laryngectomy.

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Key information

Conditions

Malignant Tumor of the Larynx Head and Neck Neoplasms Laryngeal Diseases Laryngeal Neoplasms Neoplasms Neoplasms by Site Otorhinolaryngologic Diseases Otorhinolaryngologic Neoplasms Respiratory Tract Diseases Respiratory Tract Neoplasms

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine, Mansoura University

Al Mansurah, Dakahlia Governorate, 35511, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All consecutive patients who will undergo total laryngectomy for advanced laryngeal carcinoma in the study duration.

Exclusion criteria

Presence of extra-laryngeal extension.
Patients undergoing partial pharyngectomy.
Previous neck irradiation.
Previous neck surgery.
Patients' refusal to participate in the study.

Treatment and study plan

total laryngectomy

Procedure

pharyngeal repair after total larygectomy

Primary outcomes

incidence of pharyngocutaneous fistula after total laryngectomy

Time frame: Four weeks

Secondary outcomes

subjective assessment of the swallowing function after surgery

Time frame: three months

swallowing was evaluated subjectively by applying the Eating Assessment Tool (EAT-10) questionnaire
objective assessment of the swallowing function after surgery

Time frame: Three months

swallowing was evaluated objectively by functional endoscopic evaluation of swallowing (FEES)

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Nov 21, 2025
Registry last updated: Nov 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed