Skip to main content
OpenTrials
Completed

NCT Number: NCT05813613

Role of Artificial Intelligence in Predicting Muscle Fatigue Using Virtual Reality Training

The goal of this observational predicted study is to predict muscle fatigue using a specific AI algorithm in healthy vs post Covid-19 infected individuals. The main question it aims to answer is:

Can Artificial Intelligence be used as a reliable source of predicting localized muscle fatigue in healthy vs post Covid-19 infected individuals?

Participants will be divided into two groups: A healthy group and a post Covid-19 group.

* Each group will undergo a familiarization process before the start of the exercises. * Then, each group will perform squatting exercises guided by the kynpasis virtual reality apparatus. * sEMG for the vastus lateralis and rectus femories, chest expansion, and goniometric measurements of the knee will be taken during different reported fatigue levels using the Biopac system. * Groups will continue squatting while recording their subjective fatigue levels using the Borg scale. * Data will then be run through machine learning processes to produce an AI algorithm capable of predicting isolated muscle fatigue.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–49 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ahmad ElMelhat

Beirut, Lebanon

About this study

Participants were divided into two groups, one consisting of healthy individuals and another consisting of Covid-19 subjects. Both groups received a familiarization training for the exercise to be performed with 15 minutes of rest afterwards, before the start of the data collection.

Squatting exercise was performed using a virtual reality (VR) machine (kynapsis) for guidance in both groups. Squats were performed while the hands were kept in front of the bodies and the knees flexed to 90 degrees following a rhythm of two seconds for descent, two second ascent mimicking the movement done on the VR machine.

Additional variables were considered, including chest expansion, and the range of motion using an electric goniometer, all being measured and recorded using the Biopac (BIOPAC Systems, Inc., Santa Barbara, CA) that, according to evidence, possess a high-pass frequency filter and bipolar electrode system.

The muscles tested are the 3 heads of the QF muscle RF, VM, and VL. Their areas were cleaned using alcohol and shaved to reduce resistance of electrodes. Three disposable sEMG surface electrodes were placed, two of them on the muscle belly with 2.5cm distance between them, and one control electrode placed on the agonist side, the participant was asked to extend their knee and flex it against resistance to locate the lateral and medial vasti. sEMG electrodes were placed on the subdivisions of the QF muscle during the exercise. The extracted data is then run through an AI algorithm that will analyze and predict muscle fatigue.

The Borg (C-10) scale was explained to the participants and was present in front of them while performing the exercise as an outcome measure to assess the subjective muscle fatigue that once reached will end the exercise.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Non-athletic healthy individuals.
  • Avoided intense activities in the past 3 days.
  • Confirmed positive PCR test done within an interval of 1 year for Covid-19 group subjects.

Exclusion criteria

  • Being old age geriatrics (more than 50 years old).
  • Having any respiratory, cardiac, renal, neuromuscular, orthopedic, and musculoskeletal disorders.
  • Smokers and some medicinal drug users must be taken into consideration because it affects the performance and increases the fatigue levels.
  • Subjects not meeting any of the inclusion criteria.

Treatment and study plan

Squatting with the aid of Kynapsis Virtual Training apparatus.

Other

Squatting exercise was performed using a virtual reality (VR) machine (kynapsis) for guidance in both groups. Squats were performed while the hands were kept in front of the bodies and the knees flexed to 90 degrees following a rhythm of two seconds for descent, two second ascent mimicking the movement done on the VR machine.

Primary outcomes

  1. Surface electromyography

    Time frame: During the squatting exercise.

    non-invasive technique where electrodes were placed on the vastus lateralis and rectus femoris heads of the quadriceps femoris muscle, assessing it's myoelectric output. Their areas were cleaned using alcohol and shaved to reduce resistance of electrodes. Three disposable sEMG surface electrodes were placed, two of them on the muscle belly with 2.5cm distance between them, and one control electrode placed on the agonist side, the participant was asked to extend their knee and flex it against resistance to locate the lateral and medial vasti. sEMG electrodes were placed on the subdivisions of the QF muscle during the exercise. The extracted data is then run through an AI algorithm that will analyze and predict muscle fatigue.

  2. The Borg Rating of Perceived Exertion (RPE) scale

    Time frame: During the squatting exercise.

    A tool for measuring an individual's effort and exertion, breathlessness and fatigue during physical work and so is highly relevant for occupational health and safety practice. It ranges from 6 as a minimum to 20 as a maximum with 6 signifying no exertion and 20 signifying extreme maximal exertion

Secondary outcomes

  1. Chest Expansion.

    Time frame: During the squatting exercise.

    Using a respiration transducer wrapped around the subject's chest using a velcro strap that transmits expansion data to the main receiver module of the Biopac, that will be recorded on the computer.

  2. Range of motion.

    Time frame: During the squatting exercise.

    Using an electric goniometer wired on the subject's knee that will transmit signals of range of motion to the receiver module of the Biopac that will be recorded on the computer.

Sponsors and collaborators

Lead sponsor

Beirut Arab University

Other

Registry information

Official study title

Role of Artificial Intelligence in Predicting Muscle Fatigue Using Virtual Reality Training In Healthy And Post COVID19 Subjects

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Apr 14, 2023
Registry last updated
Jun 9, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.