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Completed

NCT Number: NCT06669325

Role of Apfel's Score in Predicting Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

The goal of this observational study is to assess the role of Apfel's score in predicting postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis. The main questions it aims to answer are:

1. Does Apfel's score accurately predict the occurrence of PONV after laparoscopic cholecystectomy? 2. Which components of Apfel's score are most strongly associated with PONV?

Participants will undergo laparoscopic cholecystectomy under general anesthesia. Researchers will calculate each participant's Apfel score preoperatively, and postoperative outcomes, such as nausea and vomiting, will be monitored for 24 to 48 hours. Researchers will compare PONV incidence among patients with varying Apfel scores to determine if higher scores correlate with a higher risk of PONV.

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Key information

Conditions

APFEL RİSK SCORE Pathological Conditions, Signs and Symptoms Post Operative Nausea and Vomiting (PONV) Signs and Symptoms Signs and Symptoms, Digestive Vomiting

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

National Medical College and Teaching Hospital, Birgunj

Birgunj, Madesh, Nepal

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18 to 90 years.
  • Patient scheduled for elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
  • Patients who provided written informed consent to participate in the study.

Exclusion criteria

  • Patients receiving prophylactic antiemetic medications prior to surgery.
  • Patients on opioid analgesics for reasons other than the surgical procedure.
  • Pregnant women.
  • Patients whose laparoscopic cholecystectomy was converted to open cholecystectomy during the operation.

Treatment and study plan

Primary outcomes

  1. Incidence of Postoperative Nausea and Vomiting (PONV)

    Time frame: Assessed for 24 hours post-surgery.

    The number of patients who experience nausea and/or vomiting within 24 hours after laparoscopic cholecystectomy.

Secondary outcomes

  1. Relationship Between Apfel's Score and PONV Incidence

    Time frame: Assessed for 24 hours post-surgery.

    Evaluating the correlation between the Apfel's score (0-4) and the likelihood of PONV in patients after surgery.

Sponsors and collaborators

Lead sponsor

National Medical College Birgunj

Other

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Nov 1, 2024
Registry last updated
Nov 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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