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Completed

NCT Number: NCT04969640

Role of Anterior Segment Optical Coherence Tomography in Infectious Keratitis

To evaluate the role of anterior segment optical coherence tomography in follow up of infectious keratitis and assessment of response to treatment.

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Key information

Conditions

Infective Keratitis

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine

Minya, Egypt

About this study

50 patients with proven infectious keratitis clinically will be included in the study.

The following will be performed for all patients in initial visit and follow up:

  • Slit lamp examination and photography.
  • Visual acuity assessment.
  • Anterior segment optical coherence tomography.
  • The central corneal thickness (CCT) (extracted from pachymetry map),
  • Minimal corneal thickness (MCT) (extracted from pachymetry map)
  • Corneal thickness at the site of the lesion (CTL) (extracted from pachymetry map or the sum of STL+ CETL)
  • Stromal thickness at the center of the lesion (STL) stromal lesion (extracted from stromal map)
  • Corneal epithelial thickness over the stromal lesion (CETL) at the center of the lesion (extracted from epithelial map)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Any case with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

Exclusion criteria

  • Cases with healed infectious keratitis.
  • Cases presented from the start with severe corneal affection and melting.

Treatment and study plan

optical coherence tomography

Other

Anterior segment optical coherence tomography examination of corneas with infective keratitis

Primary outcomes

  1. criteria of lesion on optical coherence tomography

    Time frame: 1 month

    Localiztion, depth of infiltration area in microns

  2. width of lesion on optical coherence tomography

    Time frame: 1 month

    width of infiltration in microns

Sponsors and collaborators

Lead sponsor

Minia University

Other

Registry information

Official study title

Role of Anterior Segment Optical Coherence Tomography in Staging and Evaluation of Treatment Response in Infectious Keratitis

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jul 21, 2021
Registry last updated
Mar 29, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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