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Completed

NCT Number: NCT03043157

Rocuronium Effective Dose for Laparoscopic Cholecystectomy

This is an adaptative study where each participant's rocuronium dose will depend on the previous patient's response, being higher if it was not enough and lower if it was more than enough.

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Key information

Conditions

Muscle Relaxation

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Hospital das Forças armadas

Brasília, Federal District, 700000000, Brazil

About this study

Rocuronium is one of the most used neuromuscular blockers to help intubation and to relax abdominal wall for laparoscopic surgery.

Rocuronium intubation dose can be enough for intubation but not last enough for excellent laparoscopic conditions. There is little variation in time from anesthesia induction to the end of the laparoscopy for cholecystectomy and avoiding excess rocuronium dose can help providing excellent conditions and fast track extubation.

Dixon's up-and-down method will guide this dose-finding study for the ED50.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • general anesthesia

Exclusion criteria

  • deny participation

Treatment and study plan

Rocuronium

Drug

intravenous rocuronium infusion

Primary outcomes

  1. Excellent laparoscopic conditions

    Time frame: 30 minutes

    Subjective laparoscopic conditions for surgery, assessed by the main surgeon, as excellent or not

Sponsors and collaborators

Lead sponsor

Brasilia University Hospital

Other

Registry information

Official study title

Rocuronium ED50 for Excellent Laparoscopic Conditions for Cholecistectomy: Dose-finding Adaptative Clinical Trial

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Feb 3, 2017
Registry last updated
Sep 13, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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