Robot-Assisted Radical Prostatectomy: the HOOD Technique Versus Standard Anterior Reconstruction

This prospective, non-randomized cohort study included consecutive patients undergoing robotic-assisted laparoscopic radical prostatectomy (RARP) between January 2024 and January 2026 following ethics committee approval. Patients with clinically localized prostate cancer eligible for bilateral nerve-sparing surgery were enrolled. Two surgical techniques-anterior-posterior reconstruction (APR) and the HOOD technique-were compared. All procedures were performed by a single high-volume surgeon at a tertiary referral center. The primary endpoint was early urinary continence recovery, assessed at catheter removal and at 3, 6, and 12 weeks postoperatively. Secondary outcomes included postoperative complications, positive surgical margin rates, and early oncological outcomes.

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Key information

Conditions

Prostate Cancer (Adenocarcinoma) Adenocarcinoma Carcinoma Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Male Urogenital Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Prostatic Diseases Prostatic Neoplasms Urogenital Diseases Urogenital Neoplasms

Age range

40 year–75 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Ankara Universtity School of medicine department of urology

Ankara, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

life expectancy >10 years,
clinically organ confined disease (cT1-cT2),
biopsy ISUP GG ≤3,
total serum prostate-specific antigen (PSA) ≤10 ng/ml
normal preoperative continence and potency

Exclusion criteria

high risk prosatate cancer
cN1
M1 prostate cancer (according to preoperative GA68 PSMA PET CT)
pre-existing urinary incontinence,
previous prostatic, urethral, bladder neck surgery
neoadjuvant therapy
prior pelvic radiotherapy

Treatment and study plan

Prostatectomy with anterior-posterior renconstruciton

Procedure

Prostatectomy with anterior-posterior reconstruction involves restoration of both the posterior musculofascial plate and the anterior periurethral support structures during vesicourethral anastomosis, aiming to re-establish normal pelvic anatomy and improve early postoperative urinary continence following radical prostatectomy.

Prostatectomy with HOOD techinque

Procedure

Prostatectomy with the HOOD (Hood technique) is a nerve-sparing approach in which the anterior periprostatic structures, including the detrusor apron and puboprostatic ligaments, are preserved to maintain anterior urethral support and neurovascular integrity, with the aim of improving early urinary continence and functional recovery after radical prostatectomy.

Primary outcomes

Functional outcomes

Time frame: 3 weeks , 6 weeks and 12 weeks after surgery.

The Urinary continance recovery rates at the catheter removal, and subsequently at 3 weeks , 6 weeks and 12 weeks after surgery.

Sponsors and collaborators

Lead sponsor

Araz Musaev

Other

Registry information

Official study title

Early Functional Outcomes After Robot-Assisted Radical Prostatectomy: A Prospective Comparison of the HOOD Technique Versus Standard Anterior Reconstruction

Important dates

Study start: 2024
Primary completion: 2026
Study completion: 2026
First posted: Feb 18, 2026
Registry last updated: Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed