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Completed

NCT Number: NCT02794311

Risk Factors Associated With Binge Drinking Behaviors Among College Students

The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults. Results will help identifying more precisely vulnerability factors associated with this pattern of alcohol consumption and guiding prevention efforts.

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Key information

Conditions

Binge Drinking Alcohol Drinking Alcohol-Related Disorders Behavior Chemically-Induced Disorders Drinking Behavior Mental Disorders Substance-Related Disorders

Age range

18 year–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chu Reims

Reims, 51092, France

About this study

Binge drinking behavior is characterised by speed of drinking on a particular occasion, frequency of drunkenness during the most recent six month period, and the percentage of times getting drunk when drinking. The prevalence of weekly binge drinking among European Union drinkers in 2009 was reported to be 28% of the student population, and 33% among all young people aged 15-24. The consequences of this behavior are multiple and often dramatic, they include: academic failure, violent acts, rape, domestic or road accidents. The study aims to identify vulnerability factors associated with binge drinking. The protocol explores the psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI) patterns associated with binge drinking behavior.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Males or females
  • Right-handed
  • Aged 18-25 years
  • Native French speaker, able to read French and complete study evaluations
  • Caucasian
  • Able to provide informed written and verbal consent

Exclusion criteria

  • A significant general medical illness, including neurological disorders, mental retardation or head trauma
  • Depression, bipolar disorder, schizophrenia or schizoaffective disorder diagnostic according to DSM-IV
  • Handling of psychotropics substances
  • A sensorial impairment (visual and/or hearing)
  • Women who are pregnant
  • Contraindication to the use of MRI (pacemaker, metal in their body)

Treatment and study plan

Alcoolpredict

Other

psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI)

Primary outcomes

  1. Neuropsychological test : Mini International Neuropsychiatric Interview (M.I.N.I)

    Time frame: day 1

  2. Neuropsychological test : Wisconsin Card Sorting Test (WCST)

    Time frame: V2(3 weeks later)

  3. Genetics tests (Single Nucleotide Polymorphism)

    Time frame: V2(3 weeks later)

  4. MRI - signal BOLD (" Blood Oxygen Level Dependant ").

    Time frame: V3(up to 2 month)

  5. Neuropsychological test : Family Informant Schedule and Criteria (FISC)

    Time frame: day 1

  6. Neuropsychological test : Alcohol Use Questionnaire

    Time frame: day 1

  7. Neuropsychological test :Trail Making Test, partie A et B

    Time frame: V3(up to 2 month)

  8. Neuropsychological test : Plus/Minus Test

    Time frame: V3(up to 2 month)

  9. Neuropsychological test :Go/No-Go

    Time frame: V3(up to 2 month)

Sponsors and collaborators

Lead sponsor

CHU de Reims

Other

Registry information

Official study title

AlcoholPredict: Neuropsychology, Brain Imaging and Genetic Polymorphisms in Binge Drinking

Acronym: AlcoolPredict

Important dates

Study start
2015
Primary completion
2019
Study completion
2019
First posted
Jun 9, 2016
Registry last updated
Jan 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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