Risk Factors and Predictive Model for Inflammatory Polyps in Ureteral Stones

This is a single-center, observational study including a retrospective cohort and a prospective validation cohort. The study aims to identify independent risk factors for inflammatory ureteral polyps in patients with ureteral calculi and develop a preoperative predictive model. The retrospective part will analyze clinical and imaging data of patients treated at the First Hospital of Jilin University between 2018 and 2025. The prospective part is currently recruiting participants to validate the model. The primary outcome is the intraoperative diagnosis of inflammatory ureteral polyps.

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Key information

Conditions

Ureteral Calculi Calculi Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Male Urogenital Diseases Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Ureteral Diseases Ureterolithiasis Urinary Calculi Urogenital Diseases Urolithiasis Urologic Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

The First Hospital of Jilin University

Changchun, Jilin, 130021, China

Location status: Recruiting

Location contact

Yanbo Wang

CONTACT

[email protected]

13756469518

About this study

This is a bicentric bidirectional cohort study; retrospective cohort (n=629) has been fully enrolled, prospective cohort is ongoing consecutive enrollment.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 18 years or older undergoing ureteroscopic surgery for ureteral calculi at the First Hospital of Jilin University.
Complete clinical and imaging data available.

Exclusion criteria

Patients with bilateral ureteral calculi.
Patients with preoperative nephrostomy or indwelling ureteral stent.
Patients with a history of ureteral or bladder cancer.
Patients with congenital ureteral anomalies or previous ureteral surgery.
Patients with severe coagulation disorders or contraindications to ureteroscopy.
Patients unable to provide informed consent.

Treatment and study plan

Primary outcomes

Number of Participants with Intraoperatively Confirmed Inflammatory Ureteral Polyps

Time frame: At the time of ureteroscopic surgery

The primary outcome is the presence or absence of inflammatory ureteral polyps confirmed by intraoperative pathology or direct visualization during ureteroscopy.

Sponsors and collaborators

Lead sponsor

The First Hospital of Jilin University

Other

Registry information

Official study title

Risk Factors and Development of a Predictive Model for Stone-Associated Inflammatory Ureteral Polyps: A Retrospective Cohort Study With Prospective Validation

Acronym: UROLITH-POLYP

Important dates

Study start: 2018
Primary completion: 2027
Study completion: 2027
First posted: Apr 30, 2026
Registry last updated: Jun 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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