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NCT Number: NCT04047329

Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate

This study examined the risk factors and the influence of the type of anesthetic used during transurethral resection of the prostate (TURP) on subsequent incidence of myocardial infarction (MI).

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Key information

Conditions

Anesthesia Cardiovascular Diseases Heart Diseases Infarction Ischemia Myocardial Infarction Myocardial Ischemia Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Transurethral Resection of Prostate Syndrome Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

About this study

This study utilized a population-based, nationwide dataset to evaluate the risk factors of MI for patients with benign prostate hypertrophy (BPH) who received TURP. Besides, The study also compared the different effects of general anesthesia (GA) and neuraxial anesthesia (NA) on the incidence of MI within 6 and 12 months after TURP.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients receiving TURP surgery (1998-2012)

Exclusion criteria

  • Patients without anesthesia records
  • Patients receiving both general and neuraxial anesthesia
  • Mortality within 12 months of TURP

Treatment and study plan

general anesthesia or neuraxial anesthesia

Other

Primary outcomes

  1. Postoperative myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    Patients experienced myocardial infarction after transurethral resection of the prostate (TURP)

  2. Postoperative myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    Patients experienced myocardial infarction after transurethral resection of the prostate (TURP)

  3. Patient's age (year-old) that developed post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze age distribution of patients with post-TURP myocardial infarction

  4. Patient's age (year-old) that developed post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze age distribution of patients with post-TURP myocardial infarction

  5. Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed Diabetes Mellitus rate in patients who had myocardial infarction after the surgery of TURP.

  6. Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed Diabetes Mellitus rate in patients who had myocardial infarction after the surgery of TURP.

  7. Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed disorders of lipoid metabolism rate in patients who had myocardial infarction after the surgery of TURP.

  8. Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed disorders of lipoid metabolism rate in patients who had myocardial infarction after the surgery of TURP.

  9. Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed gout rate in patients who had myocardial infarction after the surgery of TURP.

  10. Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed gout rate in patients who had myocardial infarction after the surgery of TURP.

  11. Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed hypertension rate in patients who had myocardial infarction after the surgery of TURP.

  12. Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed hypertension rate in patients who had myocardial infarction after the surgery of TURP.

  13. Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed heart disease rate in patients who had myocardial infarction after the surgery of TURP.

  14. Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed heart disease rate in patients who had myocardial infarction after the surgery of TURP.

  15. Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed stroke rate in patients who had myocardial infarction after the surgery of TURP.

  16. Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed stroke rate in patients who had myocardial infarction after the surgery of TURP.

  17. Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed liver cirrhosis rate in patients who had myocardial infarction after the surgery of TURP.

  18. Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed liver cirrhosis rate in patients who had myocardial infarction after the surgery of TURP.

  19. Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed chronic obstructive pulmonary disease rate in patients who had myocardial infarction after the surgery of TURP.

  20. Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed chronic obstructive pulmonary disease rate in patients who had myocardial infarction after the surgery of TURP.

  21. Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarction

    Time frame: within 6 months after the first admission for TURP

    We analyze pre-operative diagnosed asthma rate in patients who had myocardial infarction after the surgery of TURP.

  22. Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarction

    Time frame: within 12 months after the first admission for TURP

    We analyze pre-operative diagnosed asthma rate in patients who had myocardial infarction after the surgery of TURP.

Secondary outcomes

  1. Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURP

    Time frame: within 6 months after the first admission for TURP

    Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURP

  2. Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURP

    Time frame: within 6 months after the first admission for TURP

    Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURP

  3. Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURP

    Time frame: within 12 months after the first admission for TURP

    Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURP

  4. Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURP

    Time frame: within 12 months after the first admission for TURP

    Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURP

Sponsors and collaborators

Lead sponsor

Chang Gung Memorial Hospital

Other

Registry information

Official study title

Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate: a Nationwide Database Case Control Study

Important dates

Study start
1998
Primary completion
2012
Study completion
2016
First posted
Aug 6, 2019
Registry last updated
Aug 7, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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