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Completed

NCT Number: NCT05355324

Risk Factor for Readmission and Death of Lower Respiratory Infections in Older Adults

Lower respiratory tract infection(LRTI) is a prevalent disease that threatens the health of older people worldwide. Anemia is also a common disorder in the elderly, and its prevalence increases significantly with age. Most factors that contribute to the development of anemia are improvable. Therefore, we investigated whether anemia was a risk factor for LRTI-caused readmission and death in the elderly occurring within 1 year of discharge from the hospital.

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Key information

Conditions

Lower Respiratory Infection Anemia Death Hematologic Diseases Hemic and Lymphatic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Readmission

Age range

80 year–100 year

Sex eligibility

All sexes

Study type

Observational

About this study

Objectives: To investigate the effect of anemia on readmission and deaths in the older adults following lower respiratory tract infection (LRTI)-caused hospitalization.

Design: A retrospective cohort study. Setting and Participants: Older patients (age: ≥ 80 years) hospitalized at the Department of Geriatrics, from March 2016 to December 2019 to undergo treatment for LRTIs were included.

Methods: The patients were divided into two groups (anemia and non-anemia) based on the level of hemoglobin. They were kept under observation till the occurrence of mortality event or 1 year after discharge. The primary follow-up outcome was LRTI-caused readmission and/or death.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 80 years
  • lower respiratory tract infection

Exclusion criteria

  • Died at the time of first admission
  • Active malignancy
  • Tuberculosis
  • Anemia caused by gastrointestinal bleeding of unknown origin
  • Achalasia of the cardia
  • Could not be followed up after discharge
  • Data were missing

Treatment and study plan

No intervention

Other

no intervention

Primary outcomes

  1. Number of Patients with Readmission and/ or Death Caused by Lower Respiratory Tract Infection(LRTI) within One Year of Discharge

    Time frame: March 2016 to 27 December 2019

    Number of Patients with Readmission Caused by LRTI within One Year of Discharge. Number of Patients with Death Caused by LRTI within One Year of Discharge.

Sponsors and collaborators

Lead sponsor

Beijing Tongren Hospital

Other

Registry information

Official study title

Anemia is a Risk Factor for Readmission and Death of Lower Respiratory Infections in Older Adults

Important dates

Study start
2016
Primary completion
2019
Study completion
2021
First posted
May 2, 2022
Registry last updated
May 2, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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