Skip to main content
OpenTrials
Completed

NCT Number: NCT05260723

RISE - Reduce Sitting Time Among Breast Cancer Survivors

This 3-month study will test whether a program to reduce sitting time, for breast cancer survivors experiencing some physical limitations, can improve their physical function and other important aspects of quality of life.

Completed

Looking for future studies?

Notify Me

Key information

Age range

50 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Moores UCSD Cancer Center

La Jolla, California, 92093, United States

About this study

Many cancer survivors experience long-term physical problems following their cancer treatments and can often seem much older than same age peers who were never treated for cancer. This is known as accelerated aging. One way to improve accelerated aging is to increase moderate to vigorous intensity exercise; however, for many cancer survivors, especially those with physical limitations, increasing exercise levels is not possible. Another potential way to improve accelerated aging may be to decrease the amount of time spent sitting. Long periods of sitting are related to many physical and health problems. Cancer survivors spend more than 9 hours a day sitting and often increase the amount they sit after their cancer treatments. This study could help identify realistic intervention targets for many cancer survivors and be used to guide recommendations for improving physical function and quality of life after cancer.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Breast cancer survivors (stages I-IV) at least 1 year post active treatment (e.g., chemotherapy, radiotherapy)
  • Breast cancer was treated with chemotherapy, radiation, immunotherapy, and/or endocrine therapy
  • self-report difficulties with physical function
  • self-report low levels of moderate to vigorous physical activity
  • self-report high levels of sitting time

Exclusion criteria

  • medical condition that interferes with ability to safely stand or stay balanced
  • other cancer diagnoses that occurred after their breast cancer diagnosis
  • Stage IV breast cancer with brain metastases or less than 12 months life-expectancy
  • unable to commit to a 3-month study

Treatment and study plan

Behavioral: Sit Less

Behavioral

The Sit Less arm uses habit formation, social cognitive theory, and motivational interviewing techniques to support behavior change and includes: 1) 7 health coaching sessions to set personalized goals and review progress; 2) wearing an activPAL (thigh worn accelerometer that measures sitting time); 3) intervention tools to support behavior change (e.g., standing desk, wrist worn monitor).

Primary outcomes

  1. Retention rate of enrolled participants

    Time frame: 3 months

    Percent of participants returning for the 3 month measures

Secondary outcomes

  1. 4 meter walk test

    Time frame: 3 months

    Measure of physical functioning

  2. 30-second Sit-to-Stand Test

    Time frame: 3 months

    Measure of physical functioning

  3. Timed Up and Go (TUG)

    Time frame: 3 months

    Measure of physical functioning

  4. Patient Reported Measurement Information System - Physical Function

    Time frame: 3 months

    Measure of Self-Report Physical Function, standardized T-score, higher scores indicated better functioning

Sponsors and collaborators

Lead sponsor

University of California, San Diego

Other

Registry information

Official study title

RISE - A Pilot Study to Reduce Sitting Time Among Breast Cancer Survivors

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Mar 2, 2022
Registry last updated
May 12, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.