Right Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) Findings

Systemic RV hypertrophy and impaired systolic function occur after atrial switch (AS) in d-transposition of the great arteries (d-TGA). Echocardiography has limitation in the assessment of the right ventricle (RV).

In this study the investigators sought to evaluate systemic RV myocardial mass and function after AS for d-TGA and to analyze the role of excessive hypertrophy for ventricular function under special consideration of the interventricular septal (IVS) movement.

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Key information

Conditions

Right Ventricular Hypertrophy Cardiomegaly Cardiovascular Diseases Heart Diseases Heart Failure Hypertrophy Hypertrophy, Right Ventricular Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms d-TGA

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Leipzig - Heart Center

Leipzig, 04289, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Eligibility criteria were an AS operation in childhood for correction of d-TGA and the absence of associated hemodynamically significant heart defects.

Exclusion criteria

Exclusion criteria were usual CMR contraindications such as ferromagnetic metallic implants.

Sponsors and collaborators

Lead sponsor

University of Leipzig

Other

Registry information

Official study title

Right Ventricular Hypertrophy After Atrial Switch Operation and Its Role in a Systemic RV: Normal Adaptation Process or Risk Factor? A Cardiovascular Magnetic Resonance Study

Important dates

Study start: 2007
Primary completion: 2011
Study completion: 2011
First posted: Sep 8, 2011
Registry last updated: Sep 8, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed