Cairo University
Cairo, 12613, Egypt
Location status: Recruiting
NCT Number: NCT07642193
This study aims to compare time of first request of analgesia among patients undergoing rhomboid intercostal sub-serratus plane block versus external oblique intercostal block for perioperative pain management in open nephrectomy.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Not applicable
Cairo, 12613, Egypt
Location status: Recruiting
Open nephrectomy is a common surgery usually performed for malignant and non-malignant renal pathologies. Open nephrectomy incision is associated with a high incidence of intense immediate postoperative pain and chronic pain the months following surgery.
The rhomboid intercostal block has previously been used for pain management in thoracic wall surgery.
Subserratus plane block in the treatment of post-abdominal surgical pain and the combination of the two blocks was subsequently renamed the "RISS block". The nerves targeted by the RISS block include the lateral cutaneous branches of the ventral branches of the thoracic intercostal nerves, located between the rhomboid muscle and the intercostal muscles, and deep into the scapula serratus anterior muscle. RISS block provides analgesia from T4 to T9 thoracic dermatomes and has been used in postoperative pain management for thoracic surgeries and upper abdominal surgeries.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients will receive the rhomboid intercostal subserratus plane block.
Patients will receive the external oblique intercostal block.
Patients will not receive any interventions (Intravenous morphine 0.1mg/kg after induction of general anesthesia).
Time frame: 24 hours postoperatively
Time of first request of analgesia will be recorded from the end of surgery till first dose of morphine administrated.
Time frame: 24 hours postoperatively
Heart rate will be noted immediately on arrival and at 0, 4, 8, 12, 18 and 24 h postoperatively.
Time frame: 24 hours postoperatively
Mean arterial blood pressure will be noted immediately on arrival and at 0, 4, 8, 12, 18 and 24 h postoperatively.
Time frame: 24 hours postoperatively
Fentanyl 0.5 μg / kg will be given in case of heart rate or mean arterial blood pressure ≥ 20% of the baseline
Time frame: 24 hours postoperatively
Intravenous morphine (3 mg) will be provided as rescue of analgesia. The total amount of morphine given in 24 h will be recorded.
Time frame: 24 hours postoperatively
Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS) score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable"). NRS will be recorded at 30 minutes, 2,4, 8, 12, 16, 24 hours postoperatively.
Time frame: 24 hours postoperatively
Incidence of block related complications such as local anesthetic toxicity, hematoma formation, and pneumothorax will be recorded.
Contact information is provided by the study sponsor or research team.
Cairo University
Other
Ultrasound Guided Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open Nephrectomy: Randomized Controlled Study
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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