Shirley Ryan AbilityLab
Chicago, Illinois, 60611, United States
NCT Number: NCT06510023
A study measuring rewards sensitivity in individuals with acquired brain injury at an acute rehabilitation level.
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Notify Me18 year–80 year
All sexes
Interventional
Not applicable
Chicago, Illinois, 60611, United States
Individuals in acute rehabilitation following acquired brain injury journal (ABI) and aged-matched, non-injured controls will be recruited for this study.
Testing sessions will take place in a private treatment room at the Shirley Ryan AbilityLab and required 45 minutes to complete. Upon entering the room, participants will be greeted, electrodes placed on the participant's fingers to record their electrodermal activity, and participants will provide demographic information. Participants will then be instructed about how to respond on the Cued Reinforcement Response Time task (CRRT, see description below), and complete the task on a laptop computer while their electrodermal activity is being recorded. In this task, they are instructed to respond as quickly and accurately as possible, and will be informed that they will receive a monetary reward based on their accuracy at the completion of the task. Finally, participants will complete 3 self-report measures: (1) explicit level of motivation was measured in a post-study survey which included two items from the Sensitivity to Punishment and Sensitivity to Reward Questionnaire, (SPSRQ); (2) Reward sensitivity was evaluated using the Reward Responsiveness Scale , and (3) depression was evaluated using the Patient Health Questionnaire (PHQ-8) survey. At the end of the session, the electrodes will be removed, and participants will be debriefed and provided their monetary reward
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Healthy participants
Exclusion criteria
Healthy Participants
Three different types of rewards were presented to both groups during the computerized task: one dollar, one penny, and no reward.
Time frame: 15 minutes
Accuracy (percentage of correct responses) in a Cued Response Reaction task
Time frame: 15 minutes
Response time (time in milliseconds) in a Cued Response Reaction task
Time frame: 30 minutes
Number of skin conductance responses (SCRs) before, during and after the task
Shirley Ryan AbilityLab
Other
Preserved Reward Sensitivity During Acute Rehabilitation Following Acquired Brain Injury
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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