Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06861023

Review of the Literature and Serie of Patients Who Underwent Reconstruction After Wide Local Excision of Nail Apparatus for Melanoma

Melanomas of the nail bed are often diagnosed at the locally advanced stage. The standard treatment was amputation of the finger or toe, but it has now been established that enlarged excision of the nail plate is sufficient under certain conditions. Reconstruction of the nail system can be performed by several techniques. Here, the investigators present a series of patients reconstructed by INTEGRA (dermal matrix) and skin graft

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Melanoma Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Germ Cell and Embryonal Neoplasms, Nerve Tissue Neuroectodermal Tumors Neuroendocrine Tumors Nevi and Melanomas Skin Diseases Skin Neoplasms Skin and Connective Tissue Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU NICE

Nice, Alpes Maritimes, 06000, France

Location status: Recruiting

Location contact

ELISE LUPON

CONTACT

LUC CHOUQUET

CONTACT

[email protected]

06 42 75 07 14 ext. +33

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who have undergone enlarged resection of the nail apparatus with immediate or delayed reconstruction in the setting of acral melanoma of the fingers or toes.

Exclusion criteria

  • Patients who have amputation, opposition of the pateint to the study.

Treatment and study plan

Patients who have undergone extensive nail resection with reconstruction

Other

The investigators studied a population of 10 patients who underwent nail and nail matrix excision surgery as part of the treatment of subungual melanoma, as well as the reconstruction, the investigators opted for. The specific intervention of this study is based on late postoperative questions (after 3 months)

Other names: Excision of the nail apparatus with flap reconstruction or INTEGRA + skin graft.

Primary outcomes

  1. Functional and cosmetic patient satisfaction

    Time frame: 3 months minimum postoperative

    Scores AOFAS (feet)(score ranging from 0, maximum disability, to 90, no disability), Scores QUICK DASH(score ranging from 0, no disability, to 100, maximum disability) and Mayowrist score (hands)(score ranging from 0, maximum disability, to 100, no disability)

Secondary outcomes

  1. Post-operative complications

    Time frame: 3 months minimum postoperative

    Presence or absence of Postoperative complications (inclusion cyst, nail spicule, need for repeat surgery).

  2. Recurrence of the disease

    Time frame: 3 months minimum postoperative

    Recurrence of the disease.

Study contacts

Contact information is provided by the study sponsor or research team.

ELISE LUPON

CONTACT

[email protected]

06 26 30 63 23 ext. + 33

LUC CHOUQUET

CONTACT

[email protected]

06 42 75 07 14 ext. +33

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Official study title

Review of the Literature and Retrospective, Single-centre Study of a Series of Patients Who Underwent Reconstruction After Complete Nail Resection.

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 6, 2025
Registry last updated
Mar 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.