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NCT Number: NCT07068789

Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia

This interventional prospective study aims to assess the effectiveness of single vessel versus multiple vessel infrapopliteal angioplasty in patients with chronic threatening limb ischemia . The study compares limb salvage rates and clinical outcomes across two groups over a defined follow up period

Recruiting

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Key information

Conditions

Chronic Limb Threatening Ischemia Arterial Occlusive Diseases Arteriosclerosis Atherosclerosis Cardiovascular Diseases Chronic Disease Chronic Limb-Threatening Ischemia Disease Attributes Infrapopliteal Arterial Occlusive Disease Ischemia Pathologic Processes Pathological Conditions, Signs and Symptoms Peripheral Arterial Disease Peripheral Vascular Diseases Vascular Diseases

Age range

40 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine of Sohag

Sohag, Sohag Governorate, 82511, Egypt

Location status: Recruiting

Location contact

Mahmoud Elsaedy, master student

CONTACT

[email protected]

+0201060150246

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

1. patients aged 40 years or older 2. patients with Rutherford category "4" and "5" 3. patients with angiographic evidence of infrapopliteal vessel occlusive disease -

Exclusion criteria

  • patients who refuse to participate in the study
  • patients with isolated proximal arterial disease (e.g SFA or popliteal ) without infrapopliteal involvement
  • patients who develop acute thrombosis , flow limiting dissection or perforation in the infrapopliteal arteries during intervention -

Treatment and study plan

Balloon angioplasty

Procedure

endovascular angioplasty of infrapopliteal arteries performed using standard balloon catheters under fluroscopic guidance to restore blood flow to the ischemic area

Primary outcomes

  1. limb salvage rate

    Time frame: 6 months ( with optional follow up at 12 months )

    percentage of patients who remain free from major lower limb amputation during the period of follow up after angioplasty

  2. limb salvage rate

    Time frame: 6 months ( with optional follow up at 12 months )

    percentage of patients who avoid major amputation during the period of follow up following angioplasty procedure

Study contacts

Contact information is provided by the study sponsor or research team.

Mahmoud Abdelrahman hafez, Master's student

CONTACT

[email protected]

+0201060150246

Mahmoud El-saedy, MB BCh ( candidate )

CONTACT

[email protected]

+0201120908609

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Revascularization of Single Versus Multiple Infrapopliteal Vesseles in Chronic Limb Threatening Ischemia : Limb Salvage Rate

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 16, 2025
Registry last updated
Jul 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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