Revascularisation of Autotransplanted Teeth

Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection

Note: The study was registered on Clinicaltrials.gov after termination of study.

Completed

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Key information

Conditions

Endodontic Disease Dental Pulp Diseases Pulp Canal Obliteration Stomatognathic Diseases Tooth Diseases

Age range

12 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Medical University of Graz

Graz, Styria, 8010, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male and female consenting and judicious young people and adults
Written consent of the participant and, if applicable, of the legal guardian after education
Planned tooth transplantation with advanced or completed root growth

Exclusion criteria

Contraindications for magnetic resonance imaging (MRI): (pronounced metal restorations, running orthodontics with metal, fixed appliance in the target jaw)
Current or past antiresorptive therapy with bisphosphonates
Further anamnestic general or local risk situation, among others: Anti-angiogenic therapy, History of local radiation therapy, severe coagulation disorder, unadjusted diabetes mellitus, malignant diseases
Acute gingivitis or advanced periodontitis
Participation in an ongoing drug trial (various drugs may distort the result, such as bisphosphonates, cortisone, chemotherapeutics, angiogenesis inhibitors)
heavy smokers (> 10 per day)
Acute or chronic infections (osteomyelitis) at the surgical site
metabolic diseases (diabetes, hyperparathyroidism, osteomalacia)
Severe kidney dysfunction, severe liver disease
Patients with high-dose corticosteroid therapy
prolonged corticosteroid or radiotherapy in the oral cavity
autoimmune diseases
Pregnant or breastfeeding women

Treatment and study plan

Primary outcomes

Survival

Time frame: 1 year

Tooth survival

Secondary outcomes

Revascularisation

Time frame: 1 year

Occurrence of Revascularisation

Sponsors and collaborators

Lead sponsor

Medical University of Graz

Other

Registry information

Official study title

Revascularisation of Autotransplanted Teeth - Retrospective Analysis of a Novel Technique

Important dates

Study start: 2021
Primary completion: 2022
Study completion: 2022
First posted: Mar 4, 2022
Registry last updated: Mar 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed