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Completed

NCT Number: NCT06012994

Retrospective Study of the Protective Effect of Gastrodin on Myocardium in Patients Undergoing Cardiac Surgery

Retrospective collection of Wuhan Union hospital from December 1,2018 to June 30,2021 to meet the entry and discharge standards. The patient 's medical record data were divided into study group and control group according to the use of gastrodin during operation. The perioperative data and prognostic outcomes in the patient 's medical records were collected and analyzed. The degree of myocardial injury and postoperative clinical outcomes were compared between the two groups.

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Key information

Conditions

Cardiac Surgical Procedures

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, 430022, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged≥18 years, regardless of gender;
  • Patients undergoing elective cardiac surgery under general anesthesia;
  • ASA grade 1 ~ 3.

Exclusion criteria

  • Suffering from more serious genetic diseases (such as immunodeficiency, thalassemia, etc.);
  • Moderate to severe malnutrition, moderate to severe anemia;
  • Persistent infection;
  • Severe preoperative underlying diseases (such as severe liver and kidney dysfunction)

Treatment and study plan

Primary outcomes

  1. The degree of myocardial injury

    Time frame: The myocardial tissue was collected during the operation. About 2 hours on average

    The myocardial tissue trimmed by the surgeon according to the surgical requirements was collected during the operation for electron microscopy observation and detection of related molecular content.

Sponsors and collaborators

Lead sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Other

Registry information

Important dates

Study start
2018
Primary completion
2021
Study completion
2023
First posted
Aug 28, 2023
Registry last updated
Aug 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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