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OpenTrials
Completed

NCT Number: NCT02308215

Retinal Therapy Guided by 3D OCT Image Analysis

The main purpose is to find a better way to predict the timing of treatments given to patients with Wet Age-related macular degeneration using image analysis.

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Key information

Conditions

Age-Related Macular Degeneration Choroid Diseases Choroidal Neovascularization Eye Diseases Macular Degeneration Metaplasia Neovascularization, Pathologic Pathologic Processes Pathological Conditions, Signs and Symptoms Retinal Degeneration Retinal Diseases Uveal Diseases

Age range

45 year–120 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Iowa Hospitals Dept of Ophthalmology

Iowa City, Iowa, 52246, United States

About this study

The study focuses on making better use of advanced three-dimensional imaging and analysis to allow physicians to know when a treatment is being effective and thus not overuse it. The study will examine how 3-D optical coherence tomography and related image analysis can be used to assess changes in the macula and retina of patients' eyes. These changes can reveal how well a person is responding to anti-VEGF treatment and thus help doctors provide proper treatment timing and care.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • fundoscopically confirmed AMD and patient eligible for treatment with anti-VEGF

Exclusion criteria

  • Patients with a CNV due to other causes (OHS, trauma)
  • eyes that have been previously treated for CNV

Treatment and study plan

Primary outcomes

  1. Measure central retinal layer thickness in µms.

    Time frame: one year

  2. Measure amount of fluid in the retina in µms.

    Time frame: one year

Sponsors and collaborators

Lead sponsor

Michael Abramoff

Other

Collaborators

  • National Eye Institute (NEI)

Registry information

Important dates

Study start
2010
Primary completion
2018
Study completion
2018
First posted
Dec 4, 2014
Registry last updated
Aug 30, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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