Point-of-care respiratory test platform
DeviceA point-of-care respiratory multiplex testing platform situated within a long-term care facility to provide rapid test results
Recruiting
NCT Number: NCT06660433
Respiratory Outbreak Mitigation in Long-Term Care Using Point-of-Care Testing
Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with delays leading to missed opportunities to implement virus-specific control measures to interrupt transmission resulting in larger outbreaks. Use of a point-of-care testing platform is a potential solution that provides faster results, but it is uncertain whether this translates into benefits for long-term care residents. This trial aims to assess whether rapid test results for respiratory pathogens (Influenza, Coronavirus disease of 2019 (COVID-19) and Respiratory Syncytial Virus) can impact the number and size of respiratory virus outbreaks in long-term care homes.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Michael Garron Hospital, Toronto, Ontario, Canada
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Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Long-term care facility engaged with an Ontario Health Team overseen by Sunnybrook Health Science Centre, Michael Garron Hospital or Humber River Health
Exclusion criteria
- No signed statement of agreement for study participation
- Pre-existing use of a point-of-care testing platform
Treatment and study plan
Existing respiratory virus testing platform
OtherCurrently used respiratory virus testing platforms
Primary outcomes
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Number of long-term care residents infected with COVID-19, Influenza, or respiratory syncytial virus (RSV)
Time frame: 7 months
The number of long-term care residents who contract Influenza, COVID-19 or RSV separated into the number of residents infected after an introduction is identified and the size of an outbreak of each virus.
Secondary outcomes
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The number of outbreaks of Influenza, COVID-19 or RSV
Time frame: 7 months
The number of Influenza, COVID-19 or RSV outbreaks as declared by the local Public Health Unit
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The number of long-term care residents infected during an outbreak of Influenza, COVID-19 or RSV
Time frame: 28 days
The number of long-term care residents with a confirmed or suspected Influenza, COVID-19 or RSV infection during each outbreak as tracked by the local Public Health Unit
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Frequency of hospital transfers for long-term care residents infected with Influenza, COVID-19 or RSV
Time frame: 14 days
The number of hospital transfers for long-term care residents with Influenza, COVID-19 or RSV
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Number of deaths in long-term care residents infected with Influenza, COVID-19 or RSV
Time frame: 28 days
The number of long-term care residents who die following an infection with Influenza, COVID-19 or RSV
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Duration of outbreaks in of Influenza, COVID-19 or RSV in long-term care facilities
Time frame: 60 days
The total duration of an outbreak of Influenza, COVID-19 or RSV as declared by the local Public Health Unit
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Secondary attack rate of high-risk exposures to each long-term care resident with Influenza, COVID-19 or RSV infection
Time frame: 28 days
The proportion of identified high risk contacts of an infected long-term care resident with Influenza, COVID-19 or RSV infection
Study contacts
Contact information is provided by the study sponsor or research team.
Christopher Kandel, MD, PhD
CONTACT
Jerome Leis, MD, MSc
CONTACT
Sponsors and collaborators
Lead sponsor
Michael Garron Hospital
Other
Collaborators
- Humber River Health
- Sunnybrook Health Sciences Centre
Registry information
Official study title
imProving Respiratory Outbreak Mitigation Through Point-of-care Testing in Long Term Care (PROMPT-LTC): A Cluster Randomized Trial
Acronym: PROMPT-LTC
Important dates
- Study start
- 2024
- Primary completion
- 2025
- Study completion
- 2026
- First posted
- Oct 28, 2024
- Registry last updated
- Dec 2, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.