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Completed

NCT Number: NCT01920100

Resource Use and Disease Course in Dementia (REDIC)

This project is based on a three-year program that aims to improve the knowledge of the socioeconomic consequences of dementia in Norway. By including patients with and without dementia in four different cohorts (from nursing homes, from memory clinics, home-dwelling persons with dementia and elderly persons without dementia), the project's aim is to describe the course of dementia, the economical cost of dementia and to look into possible risk factors for dementia.

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Key information

Conditions

Neurodegenerative Diseases Brain Diseases Central Nervous System Diseases Dementia Mental Disorders Nervous System Diseases Neurocognitive Disorders

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Bergen, Bergen, Norway

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Memory clinic sample

Inclusion criteria

  • All patients examined at a memory clinic with mild cognitive impairment or mild dementia

Exclusion criteria

  • None

In-home care sample

Inclusion criteria

  • Persons 70 years of age or older receiving in-home care from the municipality

Exclusion criteria

  • None

Nursing-home sample

Inclusion criteria

  • All persons admitted to the nursing home with an expected stay of more than four weeks.
  • Participants should be 65 years or older, unless established dementia disease, in which case younger persons also will be included

Exclusion criteria

  • Life expectancy of less than six weeks

Control sample

Inclusion criteria

  • Persons 65 years or older without any sign of dementia

Exclusion criteria

  • None

Treatment and study plan

Primary outcomes

  1. Cost of dementia

    Time frame: 3 years

    The cost of dementia is assessed with the Resource Utilization in Dementia (RUD) (Wimo et al. 2009), for a period of three years for all the four cohorts. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Secondary outcomes

  1. The course of neuropsychiatric symptoms

    Time frame: 3 years

    The course of neuropsychiatric symptoms (depression, anxiety, psychosis, aggression, apathy, and cognition, are assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

  2. Quality of Life in persons admitted to nursing homes

    Time frame: 3 years

    Quality of Life is assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

  3. Prescription of medication

    Time frame: 3 years

    Prescription of medication is recorded at baseline, and the amount of medication used is recorded throughout the study period. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

  4. DNA polymorphism

    Time frame: At baseline

    DNA samples are collected for the nursing home cohort, and they are assessed for genetic polymorphism previous associated with dementia. The results are used as covariates in the analyses of the course of the symptoms and to look for risk factors for dementia.

  5. Organizational factors of the nursing homes

    Time frame: At baseline

    Organizational factors of the nursing homes and variables associated with the staff of the nursing homes will be collected at baseline, and the data will be used to explore associations between nursing home characteristics and the course of the symptoms in the patients.

Sponsors and collaborators

Lead sponsor

Sykehuset Innlandet HF

Other

Collaborators

  • Helse Midt-Norge
  • Karolinska Institutet
  • King's College London
  • Norwegian Centre for Ageing and Health
  • Norwegian Directorate of Health
  • Norwegian University of Science and Technology
  • Oslo University Hospital
  • University Hospital, Akershus
  • University of Bergen

Registry information

Acronym: REDIC

Important dates

Study start
2009
Primary completion
2015
Study completion
2023
First posted
Aug 9, 2013
Registry last updated
Nov 24, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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