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NCT Number: NCT07466186

Resistance Training on Depression and Quality of Life in Type 1 Diabetic Women

Find out the effects of resistance training on depression, sleep quality, and quality of life in women with type 1 diabetes mellitus

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Key information

Conditions

Type 1 Diabetes Mellitus Autoimmune Diseases Diabetes Mellitus Diabetes Mellitus, Type 1 Endocrine System Diseases Glucose Metabolism Disorders Immune System Diseases Metabolic Diseases Nutritional and Metabolic Diseases

Age range

20 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Seventy-eight women aged 20 to 45 years with type 1 diabetes mellitus will be randomly assigned to either a resistance training group, which will receive both resistance and breathing exercises, or an active control group, which will receive breathing exercises only. The intervention will last for 12 weeks, with resistance exercises will be performed at moderate intensity. Outcomes will be assessed using the Beck Depression Inventory-II, the Pittsburgh Sleep Quality Index, and the Diabetes Quality of Life Questionnaire.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of type 1 diabetes for more than 5 years
  • Unchanged insulin doses for no less than three months
  • Good glycemic control, defined as glycated hemoglobin levels below 7%
  • Minimal to moderate depressive symptoms
  • Sleep quality impairment

Exclusion criteria

Presence of other types of diabetes, unstable cardiopulmonary conditions, recent neurological or musculoskeletal problems affecting exercise, pregnancy, postmenopausal status, and the use of sedatives or antidepressants.

Treatment and study plan

Resistance Exercises

Other

The program will include seven exercises targeting major muscle groups: chest press, triceps extension, and shoulder front raise for the upper limbs; back extensions and abdominal crunches for the trunk; and leg press, leg curl, and calf raise for the lower limbs.

Breathing exercises

Other

The procedure will be first demonstrated and explained to each woman prior to the first session. Starting from a crook-lying position, participants will be guided to inhale through the nose for a count of four, hold their breath for another four counts, exhale slowly through the mouth over four counts, and then pause for an additional four counts before repeating the cycle.

Primary outcomes

  1. Depression

    Time frame: Baseline and 12 weeks later

    Depression will be assessed using the Beck Depression Inventory-II

Secondary outcomes

  1. Sleep quality

    Time frame: At baseline and 12 weeks later

    Sleep quality will be assessed using the Pittsburgh Sleep Quality Index

  2. Quality of life

    Time frame: At baseline and after 12 weeks

    The Arabic version of the Diabetes Quality of Life Questionnaire will be completed by each participant to assess quality of life

Study contacts

Contact information is provided by the study sponsor or research team.

Mohammed Elhamrawy, Ph.D

CONTACT

Saher Elgayar, Ph.D

CONTACT

[email protected]

+201020429911

Sponsors and collaborators

Lead sponsor

Middle East University

Other

Registry information

Official study title

Effect of Resistance Training on Depression and Quality of Life in Type 1 Diabetic Women

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 12, 2026
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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