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OpenTrials
Completed

NCT Number: NCT02447146

Resistance Training in Patients With Parkinson's Disease.

This is a controlled trial to assess the effects of resistance training on bradykinesia and physical function in patients with Parkinson's Disease. Forty patients diagnosed with Parkinson Disease stage 1 to 3 of the Hoehn and Yahr scale took part in the study and were allocated into 2 groups; Training Group performed a 9-week RT program twice a week while the Control Group attended lectures on the disease.

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Key information

Conditions

Parkinson Disease Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinsonian Disorders Synucleinopathies

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Medical neurologist confirmation of 1-3 Hoehn and Yahr stages,
  • age between 50 and 80 years old;
  • and physician attested to participate in the resistance training program.

Exclusion criteria

  • Diagnostic of any other neurological disease, cardiovascular disease, hematologic or orthopedic disorders;
  • and motor fluctuations or severe dyskinesia that could affect their ability to perform the experimental protocol.

Treatment and study plan

Resistance training

Other

The TG performed the RT program using weight machines. Before the training period, participants underwent three weeks with eight familiarization sessions to ensure proper technique execution. The protocol aimed to workout major muscle groups and involved the following exercises: chest press, knee extension, hamstrings curl, leg press, and seated row. Training sessions lasted approximately 50-60 minutes with 2 sets of 10-12 repetitions until fatigue.

Lectures on the disease

Other

The control group attended an orientation program with lectures on health, quality of life and scientific update on disease.

Primary outcomes

  1. Bradykinesia measured with Unified Parkinson's Disease Rating Scale, section III

    Time frame: One time point; after the end of 9-week resistance training

  2. Functional Performance measured with Ten Meters Walk Test.

    Time frame: One time point; after the end of 9-week resistance training

Secondary outcomes

  1. Muscle strength measured with isokinetic peak torque.

    Time frame: One time point; after the end of 9-week resistance training

Sponsors and collaborators

Lead sponsor

University of Brasilia

Other

Registry information

Official study title

Effects of Resistance Training on Bradykinesia and Physical Function in Patients With Parkinson's Disease.

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
May 18, 2015
Registry last updated
May 18, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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