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OpenTrials
Completed

NCT Number: NCT01220037

Resistance Exercise in Healthy Men

In the present study, the effects of age and dietary intake will be assessed on myocellular characteristics during 72 hours after a resistance type exercise session.

Completed

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Key information

Conditions

Single Bout of Resistance Type Exercise Standardized Diet

Age range

18 year–85 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Maastricht University Medical Centre

Maastricht, Zuid Limburg, 6200MD, Netherlands

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy men between the ages of 18-30 or 70-85 years

Exclusion criteria

  • Subjects with a recent history or current state of cardiovascular disease, COPD, Parkinson, rheumatoid arthritis, musculoskeletal/orthopaedic disorders, renal disorder, cognitive impairment.

Treatment and study plan

Adhere to a specific standardized diet for 4 days

Behavioral

24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Primary outcomes

  1. Muscle fiber myonuclear and stem cell content

    Time frame: baseline

  2. Muscle fiber myonuclear and stem cell content

    Time frame: 12 hours after a single bout of resistance type exercise

  3. Muscle fiber myonuclear and stem cell content

    Time frame: 24 hours after a single bout of resistance type exercise

  4. Muscle fiber myonuclear and stem cell content

    Time frame: 48 hours after a single bout of resistance type exercise

  5. Muscle fiber myonuclear and stem cell content

    Time frame: 72 hours after a single bout resistance type exercise

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Registry information

Official study title

The Effect of Age and Dietary Protein Intake on Myocellular Characteristics Following a Single Bout of Resistance Exercise in Healthy Men

Important dates

Study start
2010
Primary completion
2011
Study completion
2011
First posted
Oct 13, 2010
Registry last updated
Oct 28, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.