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OpenTrials
Completed

NCT Number: NCT00986024

Resistance and/or Endurance Training, What is Most Effective in Prevention of Cardiovascular Diseases?

The aim of the present study was to evaluate the effects of aerobic interval training versus strength training or a combination of these regimes on factors comprising the metabolic syndrome in order to find the most effective exercise regime for patients with metabolic syndrome.

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Key information

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

In the Western world, approximately 25% of young to middle-aged adults have metabolic syndrome. There seem to be a strong age-dependence in the prevalence of the metabolic syndrome, but the incidence rises rapidly within adolescents and middle-aged groups and follows the development of obesity in the general population. Metabolic syndrome confers an increased risk of coronary heart disease, cardiovascular disease, and premature death; therefore, effective and affordable strategies to combat the syndrome would be of great individual and social importance.

Despite the general agreement that moderate-intensity physical activity for a minimum of 30 min five days per week or vigorous-intensity aerobic physical activity for a minimum of 20 min three days a week promote and maintain health, the optimal training regime to treat metabolic syndrome and its associated cardiovascular abnormalities remains uncertain.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Having metabolic syndrome according to international diabetes foundations definition (IDF).

Exclusion criteria

  • Unstable angina pectoris
  • Uncompensated heart failure
  • Myocardial infarction during the past 4 weeks
  • Complex ventricular arrhythmias
  • Kidney failure

Treatment and study plan

Aerobic Exercise

Behavioral

carried out 3 times per week for 12 weeks

strength training

Behavioral

carried out 3 times per week for 12 weeks

Primary outcomes

  1. proinflammatory markers

    Time frame: 12 weeks

    circulating interleukin-18 and interleukin-6

Sponsors and collaborators

Lead sponsor

Norwegian University of Science and Technology

Other

Registry information

Official study title

Strength Training Versus Aerobic Interval Training to Modify Risk Factors of the Metabolic Syndrome

Important dates

Study start
2006
Primary completion
2007
Study completion
2007
First posted
Sep 29, 2009
Registry last updated
Dec 13, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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