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OpenTrials
Completed

NCT Number: NCT01387061

Resection for Multiple Hepatocellular Carcinomas (HCC)

Surgical resection in patients with multiple hepatocellular carcinomas (HCC) remains controversial. The aim of this study was to investigate the outcome of a consecutive cohort of patients resected for multiple HCC, without macrovascular invasion, in order to identify clinically reliable parameters to select patients for surgery.

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Key information

Conditions

Hepatocellular Carcinoma Adenocarcinoma Carcinoma Carcinoma, Hepatocellular Cirrhosis Digestive System Diseases Digestive System Neoplasms Fibrosis Liver Diseases Liver Neoplasms Multiple Tumors Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Pathologic Processes Pathological Conditions, Signs and Symptoms

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Milan IRCCS Istituto Clinico Humanitas

Rozzano, Milan, MI, 20089, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with multiple HCC without macrovascular invasion on liver cirrhosis

Exclusion criteria

  • macrovascular invasion;
  • normal liver;
  • distant or lymphnodes metastasis

Treatment and study plan

hepatic resection

Procedure

surgical resection of the liver for multiple HCC

Primary outcomes

  1. Overall survival plus multivariate analysis

    Time frame: 10 years

    The primary endpoint of the study was the overall survival of patients resected for multiple HCC, and the univariate and multivariate analyses of prognostic factors for overall survival.

Secondary outcomes

  1. Disease-free survival

    Time frame: 10 years

    The secondary endpoint was the disease-free survival.

Sponsors and collaborators

Lead sponsor

University of Milan

Other

Registry information

Official study title

Hepatic Resection for Multiple Hepatocellular Carcinoma on Cirrhosis

Important dates

Study start
2001
Primary completion
2011
Study completion
2011
First posted
Jul 4, 2011
Registry last updated
Sep 20, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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