Research on the Effectiveness of Neurorehabilitation After Stroke

Inclusion criteria

• Signed written informed consent.
• Age 18 to 80 years at the time of stroke onset.
• Early rehabilitation period (up to 6 months post-stroke).
• Diagnosis of acute cerebrovascular accident confirmed by MRI or CT.
• Upper limb paresis severity between 0 and 3 on the 6-point Medical Research Council (MRC) muscle strength scale.
• Ability and willingness to comply with the study protocol.
• Demonstrated motivation for rehabilitation.

Exclusion criteria

• Montreal Cognitive Assessment scale (MoCA) score less than 10 points.
• Hamilton Depression Rating Scale (Ham-D) score greater than 18 points.
• Modified Rankin Scale (mRS) score greater than 4 points.
• Pre-existing conditions that cause decreased muscle strength or increased muscle tone in the upper limbs (e.g., cerebral palsy, traumatic brain injury) or rigidity (e.g., Parkinson's disease, contractures).
• Advanced arthritis or significant limitation of upper limb range of motion.
• Absence of part of the upper limb due to amputation for any reason.
• Any medical condition that may affect the conduct of the study or patient safety (e.g., mental illness).
• Alcohol abuse or recreational drug use within the 12 months preceding the study.
• Use of experimental medications or medical devices within the 30 days preceding the study.
• Inability to comply with research procedures, as determined by the researcher.
• The severity of the patient's condition, based on neurological or physical status, does not permit full rehabilitation.
• Visual acuity less than 0.2 in the weakest eye according to the Sivtsev visual acuity chart.
• Unstable angina and/or heart attack within the 30 days preceding the study.
• Recurrent stroke.
• Uncontrolled arterial hypertension.
• Ataxia.
• Presence of a pacemaker and/or other implanted electronic devices.
• Use of muscle relaxants.
• Peripheral neuropathy.
• Coexisting diseases in an exacerbation or decompensated stage requiring active treatment.
• Allergic reactions or other skin lesions at the EEG electrode application sites at the time of the study.
• Acute urinary tract infections.
• Acute thrombophlebitis.
• Any form of epilepsy.
• Benign and malignant neoplasms.