Research on Nutritional Risk Indexes and Inflammatory Indicators in Postoperative Complications and Prognosis of Epithelial Ovarian Cancer Patients

The goal of this observational study is to explore the influence and predictive significance of nutritional risk indicators and inflammatory indicators on postoperative complications and prognosis of patients with epithelial ovarian cancer (EOC). The main question it aims to answer is:

Can preoperative nutritional risk and inflammatory indexes predict postoperative complications? Do preoperative nutritional risk and inflammatory indexes better predict the prognosis of patients with epithelial ovarian cancer? Which index is the best predictor of postoperative complications or prognosis for patients?

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Key information

Conditions

Epithelial Ovarian Cancer Adnexal Diseases Carcinoma Carcinoma, Ovarian Epithelial Endocrine Gland Neoplasms Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Genital Neoplasms, Female Gonadal Disorders Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Ovarian Diseases Ovarian Neoplasms Urogenital Diseases Urogenital Neoplasms

Sex eligibility

Female

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

histologically confirmed primary epithelial ovarian, peritoneal, and fallopian tube cancers.
patients received comprehensive staged surgery or debulking surgery.
available data of laboratory examination within 7 days before the surgery.

Exclusion criteria

borderline ovarian tumor.
receipt of neoadjuvant chemotherapy.
presence of other conditions influencing laboratory data, like hepatitis, kidney disease, autoimmune diseases, infectious diseases, blood disease, etc.
concurrent cancer in other organs.
absence of surgery or biopsy only.
multiple staged surgeries.

Treatment and study plan

Primary outcomes

Postoperative Complications

Time frame: Within 30 days after surgery

Surgical complications within 30 days after comprehensive staging or cytoreductive surgery recorded according to the Clavien-Dindo grading system
Progression-free survival

Time frame: From the date the patient diagnosed with primary ovarian, fallopian tube, or peritoneal cancer to the date of disease progression or death or last follow-up, whichever occurred first, assessed up to 100 months.

Interval between first diagnosis and first recurrence, death, or last follow-up
Overall survival

Time frame: From the date the patient diagnosed with primary ovarian, fallopian tube, or peritoneal cancer to the date of death or last follow-up, whichever occurred first, assessed up to 100 months.

Interval between first diagnosis and death, or last follow-up

Sponsors and collaborators

Lead sponsor

Qinglei Gao

Other

Registry information

Official study title

Influence of Nutritional Risk Indexes and Inflammatory Indicators on Postoperative Complications and Prognosis of Epithelial Ovarian Cancer and Construction of Prediction Models

Important dates

Study start: 2012
Primary completion: 2023
Study completion: 2023
First posted: Jul 3, 2024
Registry last updated: Jul 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed