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Completed

NCT Number: NCT04633135

Research on Emissions, Air Quality, Climate and Cooking Technologies in Northern Ghana

REACCTING (Research on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana) is an interdisciplinary randomized cookstove intervention study in the Kassena-Nankana District of Northern Ghana. The study tests two types of biomass burning stoves that have the potential to meet local cooking needs and represent different "rungs" in the cookstove technology ladder: a locally-made, low-tech Gyapa rocket stove and the imported, highly efficient Philips gasifier stove. Intervention households were randomized into four different groups, three of which received different combinations of two improved stoves, while the fourth group serves as a control for the duration of the study. Diverse measurements assess different points along the causal chain linking the intervention to final outcomes of interest. The investigators assess stove use and cooking behavior, cooking emissions, household air pollution and personal exposure, health burden, and local to regional air quality. Integrated analysis and modeling will tackle a range of interdisciplinary science questions, including examining ambient exposures among the regional population, assessing how those exposures might change with different technologies and behaviors, and estimating the comparative impact of local behavior and technological changes versus regional climate variability and change on local air quality and health outcomes.

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Key information

Conditions

Inflammation Growth Retardation Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

0 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion

Individual Participants:

  • Classified as "rural"
  • Uses biofuel as main cooking fuel source (firewood, animal waste, crop residue/sawdust)
  • Uses borehole as main water source (to facilitate social network analysis linking household's knowledge and attitudes toward stoves to experience of social contacts);
  • Does not have electricity (to permit possible addition of lighting intervention at a later date);
  • Has a woman in household aged 18-55 and at least one child under five (since women and children are the most vulnerable to cookstove smoke and are thus the main focus of our health measures).

Clusters:

  • No more than 25% classified as urban
  • Accessible year-round (determined by field staff)
  • Having at least 10 eligible households (in line with the participant criteria above)

Exclusion:

  • Household could not be located
  • Household declined to participate

Treatment and study plan

Philips stove

Device

Philips Smokeless stove HD4012LS

Other names: Gasifier stove

Gyapa stove

Device

Wood stove made in Ghana

Other names: Rocket stove

Primary outcomes

  1. Health (Biomarkers of inflammation)

    Time frame: At baseline

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

  2. Health (Biomarkers of inflammation)

    Time frame: At 6 months

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

  3. Health (Biomarkers of inflammation)

    Time frame: At 12 months

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

  4. Health (Biomarkers of inflammation)

    Time frame: At 18 months

    Health indicators from blood spot samples (C-Reactive Protein, Sicam, sVCAM, serum amyloid A, Interleukin-1b, Interleukin-6, Interleukin-8, tumor necrosis factor alpha).

  5. Height

    Time frame: At baseline

    Height of participants

  6. Height

    Time frame: At 6 months

    Height of participants

  7. Height

    Time frame: At 12 months

    Height of participants

  8. Height

    Time frame: At 18 months

    Height of participants

  9. Weight

    Time frame: At baseline

    Weight of participants

  10. Weight

    Time frame: At 6 months

    Weight of participants

  11. Weight

    Time frame: At 12 months

    Weight of participants

  12. Weight

    Time frame: At 18 months

    Weight of participants

  13. Mid-arm circumference

    Time frame: At baseline

    Measurement of mid-upper arm circumference of participants

  14. Mid-arm circumference

    Time frame: At 6 months

    Measurement of mid-upper arm circumference of participants

  15. Mid-arm circumference

    Time frame: At 12 months

    Measurement of mid-upper arm circumference of participants

  16. Mid-arm circumference

    Time frame: At 18 months

    Measurement of mid-upper arm circumference of participants

Secondary outcomes

  1. Personal exposure to fine particulate matter (PM2.5)

    Time frame: 48 hour deployment periods

    48 hour integrated personal PM2.5 concentrations from filter measurements

  2. Personal exposure to carbon monoxide (CO)

    Time frame: 48 hour deployment periods

    Daily average and integrated personal CO concentrations

  3. Kitchen area concentrations of carbon monoxide (CO)

    Time frame: 48 hour deployment periods

    Daily average and integrated kitchen area CO concentrations

  4. Kitchen area concentrations of fine particulate matter (PM2.5)

    Time frame: 48 hour deployment periods

    48 hour integrated kitchen area PM2.5 concentrations from filter measurements

  5. Self-reported stove usage

    Time frame: At baseline

    Surveys administered to respondents (primary cooks)

  6. Self-reported stove usage

    Time frame: At 6 months

    Surveys administered to respondents (primary cooks)

  7. Self-reported stove usage

    Time frame: At 12 months

    Surveys administered to respondents (primary cooks)

  8. Self-reported stove usage

    Time frame: At 18 months

    Surveys administered to respondents (primary cooks)

  9. Stove usage as measured by devices

    Time frame: Throughout data collection period, approximately 2 years.

    Continuous stove usage indicators as measured by temperature loggers on stoves

Sponsors and collaborators

Lead sponsor

University of Colorado, Boulder

Other

Collaborators

  • Environmental Protection Agency (EPA)
  • U.S. National Science Foundation

Registry information

Acronym: REACCTING

Important dates

Study start
2012
Primary completion
2016
Study completion
2017
First posted
Nov 18, 2020
Registry last updated
Nov 18, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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