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NCT Number: NCT06978348

Research on Early Prediction Model of Ischemic Cerebrovascular Disease Based on Artificial Intelligence Technology.

Establish an artificial intelligence clinical decision support system for patients with carotid/vertebral artery cerebrovascular stenosis, early identification of patients who may have cerebral infarction. With the support of this project, it is expected that a secondary prevention clinical decision support system for chronic stroke will be established, which is likely to become an important auxiliary tool for the management of cerebrovascular diseases in the future.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Model

Shanghai, Shanghai Municipality, China

Location status: Recruiting

Location contact

Yijun Cheng

CONTACT

About this study

Stroke is a disease with a high mortality rate and incidence rate, and it is one of the main reasons for high medical expenses. Ischemic stroke accounts for approximately 85% of all subtypes of stroke. Carotid artery and vertebral artery stenosis are definite and intervenable risk factors for ischemic stroke. However, the selection of clinical intervention timing and methods for patients with cerebrovascular stenosis is limited to the rate of carotid/vertebral artery stenosis and the symptoms of the patients. Cerebral infarction caused by carotid/vertebral artery stenosis often leads to irreparable neurological deficits. Currently, there is a lack of comprehensive evaluation methods for the severity of ischemic cerebrovascular diseases such as carotid/vertebral artery stenosis, and even less a clinical decision-making system that can predict the progression of the disease. This project intends to take the demographic data and clinical information of patients with cerebrovascular stenosis from multiple centers and ethnic groups as the entry point, combine the multidisciplinary advantages of imaging, ultrasound, clinical medicine and computer science, and use artificial intelligence technology to construct a model for predicting the disease progression and the probability of adverse cardiovascular events such as stroke in patients with cerebrovascular stenosis. Based on this, the investigators' hospital intends to develop a set of secondary prevention management tools and clinical decision support systems for ischemic cerebrovascular diseases.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients undergoing vascular (carotid/vertebral artery) B-ultrasound

Exclusion criteria

Patients with missing clinical data such as medical history, cerebrovascular ultrasound results and biochemical data

Treatment and study plan

Primary outcomes

  1. Establish an artificial intelligence clinical decision support system for patients with carotid/vertebral artery cerebrovascular stenosis,Early identification of patients who may have cerebral infarction.

    Time frame: December 2025

    1.The clinical history, imaging data, blood test indicators and other data of patients who completed carotid/vertebral artery cerebrovascular ultrasound examinations from January 2012 to December 2022 were collected to establish a data set;2. This dataset was statistically analyzed in combination with the general risk factors of cerebrovascular diseases and the specific risk factors of carotid artery stenosis;3. The above-mentioned model was trained using the existing clinical database of patients with carotid and cerebrovascular stenosis in the hospital;4. Through machine learning, an artificial intelligence clinical decision support system for patients with carotid/vertebral artery stenosis is established to identify patients with early cerebrovascular stenosis who require surgical intervention, and even asymptomatic patients.

Secondary outcomes

  1. Analyze the risk factors leading to stroke

    Time frame: December 2025

    By collecting the baseline demographic data, clinical history, imaging, laboratory tests and other data of all patients who underwent carotid/vertebral artery vascular ultrasound during the period from 2012.01 to 2022.12, the risk factors causing stroke were analyzed.

Study contacts

Contact information is provided by the study sponsor or research team.

Yijun Cheng, Doc

CONTACT

[email protected]

86+15021058538

Sponsors and collaborators

Lead sponsor

Shanghai Jiao Tong University School of Medicine

Other

Registry information

Official study title

Establish an Artificial Intelligence Clinical Decision Support System for Patients With Carotid/Vertebral Artery Stenosis.

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 18, 2025
Registry last updated
May 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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