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Completed

NCT Number: NCT03767179

Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases

Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion

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Key information

Age range

18 year–35 year

Sex eligibility

Female

Study type

Observational

Primary location

Karadeniz Technical University, Medical Faculty of Medicine.

Trabzon, Ortahisar, 61000, Turkey (Türkiye)

About this study

The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease

Exclusion criteria

  • Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus)
  • Smoking
  • Rejection to participate in the study.

Treatment and study plan

study

Diagnostic Test

procalcitonin, sedimentation, CRP, leukocyte identification

Primary outcomes

  1. Serum LC

    Time frame: 01.01.2018- 15.02.2019

    Serum leukocyte count in number

  2. CRP

    Time frame: 01.01.2018- 15.02.2019

    Serum CRP level in microgram

  3. ESR

    Time frame: 01.01.2018- 15.02.2019

    Erythrocyte sedimentation rate

  4. Prokalsitonin

    Time frame: 01.01.2018- 15.02.2019

    Serum procalcitonin level in microgram

Sponsors and collaborators

Lead sponsor

Karadeniz Technical University

Other

Registry information

Official study title

Research of Serum Procalcitonin, Erythrocyte Sedimentation Rate, C-Reactive Protein And Leukocyte Levels in Fertile Missed Abortion Cases

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Dec 6, 2018
Registry last updated
Jun 26, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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