Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.

The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism.

The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.

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Key information

Conditions

Glomerulonephritis, Membranous Autoimmune Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genetic Diseases, Inborn Glomerulonephritis Hemochromatosis Immune System Diseases Iron Metabolism Disorders Iron Overload Kidney Diseases Male Urogenital Diseases Metabolic Diseases Metabolism, Inborn Errors Metal Metabolism, Inborn Errors Neonatal Diseases and Abnormalities Neonatal hemochromatosis Nephritis Nutritional and Metabolic Diseases Urogenital Diseases Urologic Diseases

Sex eligibility

Female

Study type

Observational

Primary location

Limoges University Hospital

Limoges, 87042, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Mothers having a child suffering from:

Neonatal membranous glomerulonephritis
Unexplained neonatal tubular defect
Unexplained thrombotic microangiopathy
Neonatal hemochromatosis

Exclusion criteria

Any cause explaining the child's disease

Sponsors and collaborators

Lead sponsor

University Hospital, Limoges

Other

Registry information

Important dates

Study start: 2005
Primary completion: 2013
Study completion: 2014
First posted: Sep 20, 2005
Registry last updated: Jan 15, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed