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NCT Number: NCT06074822

Research Biobank From Neuromuscular Biopsy Residues (in the Context of Care)

Neuromuscular diseases are rare diseases for which significant progress has been made in the context of diagnosis thanks to advances in molecular techniques, but the intimate mechanisms of lesion formation remain poorly understood. Advances in cellular and molecular biology, the development of a few animal models, such as transgenic mice, which make it possible to mimic human pathology have made it possible to better understand the physiopathology of these diseases. However, they still do so very imperfectly and incompletely, making it even more necessary than ever to study diseased human muscle tissue to find new avenues of research or to confirm results obtained by experimentation.

The purpose of this collection of tissue samples for neuro-muscular purposes is to collect such samples under the best conditions in order to promote basic and translational research on muscle diseases.

This is why the CHU de Bordeaux wishes to keep the remainders of samples taken as part of the treatment to constitute a collection of biological samples and associated data kept according to quality standards and in compliance with the regulations in force.

Recruiting

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Université Hospital, Bordeaux

Bordeaux, 33000, France

Location status: Recruiting

Location contact

Marie Laure NEGRIER, Pr

CONTACT

[email protected]

0557821818 ext. +33

About this study

The "COLMYONEU" project is a project to collect leftover frozen neuromuscular biopsy samples from patients taken as part of their health care at the Bordeaux University Hospital for neuromuscular disease.

Its main objective is to store, under the conditions of the CRB standard, residual biological samples from patients with neuromuscular symptoms.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients treated at Bordeaux University Hospital (neurology services, neuropediatrics), rheumatology, medical genetics for suspected neuromuscular disease.
  • Men and women are affected, adults and minors.

Exclusion criteria

  • no exclusion criteria

Treatment and study plan

Residual neuromuscular biopsy

Other

recovery of residual neuromuscular biopsy (nerve ans muscle)

Primary outcomes

  1. Constitution of a biocollection

    Time frame: 30 years

    Collection of leftover frozen neuromuscular biopsy samples from patients taken as part of their health care at the Bordeaux University Hospital for neuromuscular disease.

Study contacts

Contact information is provided by the study sponsor or research team.

Guilhem SOLE, Dr

CONTACT

[email protected]

0557821818 ext. +33

Marie Laure NEGRIER, Pr

CONTACT

[email protected]

0557821818 ext. +33

Sponsors and collaborators

Lead sponsor

University Hospital, Bordeaux

Other

Registry information

Official study title

Constitution of a Collection of Residues of Neuromuscular Biopsies From Patients Taken as Part of Their Health Care at the Bordeaux University Hospital for Neuromuscular Disease and Use for Research Projects

Acronym: COLMYONEU

Important dates

Study start
2023
Primary completion
2053
Study completion
2053
First posted
Oct 10, 2023
Registry last updated
Oct 10, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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