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OpenTrials
Completed

NCT Number: NCT06365294

Rescue Extracranial Vertebral Stenting in Tandem Occlusions

The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion. The investigators reported whether the additional rescue extracranial stenting improved clinical outcome by modified Rankin Scale (mRS) score within 3 months after the procedure

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Key information

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Can Tho SIS Hospital

Can Tho, 900000, Vietnam

About this study

Acute vertebrobasilar artery occlusion is one of the cerebrovascular diseases with high disability and mortality rates. Although mechanical thrombectomy has recently been demonstrated an effective treatment for large vessel occlusions of posterior circulation, the treatment strategies depending on the specific pathophysiology. Tandem occlusion in posterior circulation is less frequently than in anterior one, comprises severe stenosis or occlusion of the extracranial vertebral artery ipsilateral to its intracranial and basilar occlusion. The recent studies showed the benefit of the "distal-to-proximal" approach, there were many tecniques to achieved the successful recanalization. Besides, the use of Dotter technique allowed 8F guiding catheter to cross the extracranial lesions easily and save the procedural time. However, the Diagnosis 5F-Dotter, like the Dilator-Dotter, has not been mentioned in previous studies. Therefore, the aim of the our study was to assess the improvement of outcomes at 3 months posttreatment in patients receiving rescue extracranial vertebral stenting

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age > 18 years old
  • Onset to treatment time < 24 hours
  • NIHSS > 5
  • pc-ASPECTS ≥ 5

Exclusion criteria

  • Premorbid mRS > 2
  • Extensive, bilateral brain-stem infarction on neuroimaging
  • Cerebellar mass effect on neuroimaging
  • Loss to follow-up

Treatment and study plan

Rescue extracranial stenting

Procedure

Rescue extracranial stenting in tandem occlusions

Primary outcomes

  1. The good 3-month outcome rate

    Time frame: 3 months

    The good 3-month outcome rate was accessed by modified Rankin Score (mRS ≤ 2).

Sponsors and collaborators

Lead sponsor

Dr. Cuong Tran Chi

Other

Registry information

Acronym: REVET

Important dates

Study start
2020
Primary completion
2024
Study completion
2024
First posted
Apr 15, 2024
Registry last updated
Jun 11, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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