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NCT Number: NCT07437742

Reproductive Prognosis in Women Seeking Offspring After Medical or Surgical Therapy for Endometriosis

The study aims to compare the percentage of women with endometriosis who undergo PMA after medical vs surgical treatment and to describe conception patterns, pregnancy rates, and number of live vessels in women seeking offspring with endometriosis.

Recruiting

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Key information

Age range

18 year–40 year

Sex eligibility

Female

Study type

Observational

Primary location

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, MI, Italia, 20077, Italy

Location status: Recruiting

Location contact

Nicola Dr Berlanda

CONTACT

[email protected]

+39 0255031

About this study

The objective of the study is to compare how many women with endometriosis undergo PMA after medical treatment and how many after surgical treatment , then compare these data with those reported in the literature. Secondary objectives will be to describe the mode of conception ande pregnancy rate and to compare the pregnancy rate from post-surgical PMA observed in the present Italian multicenter study with that observed in the previous single-center study conducted at the Foundation. This will allow to evaluate the impact of 15 years of evolution of surgical and PMA techniques on the reproductive prognosis of women operated for endometriosis and to expand the observation to the whole Italian territory.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age <40 years at the time of offspring research
  • previous ultrasound or surgical diagnosis of endometriosis made in one of the endometriosis referral centres participating in the study
  • search for offspring after diagnosis
  • consent to the use of pseudonymised data for research purposes.

Exclusion criteria

  • women without endometriosis
  • age >=40 years at the time of the search for offspring
  • women who have undergone demolition surgery
  • women who do not wish to have offspring
  • women who have not given consent for their pseudonymised data to be used for research purposes
  • severe male infertility factor (testicular sperm retrieval)

Treatment and study plan

PMA

Other

use of Medically assisted procreation techniques (PMA)

Primary outcomes

  1. endometriosis and PMA

    Time frame: 2012 to 2021 diagnosis

    Compare the number of women who undergo PMA after medical treatment with those who undergo PMA after surgery, then compare these data with those reported in the literature

Study contacts

Contact information is provided by the study sponsor or research team.

Nicola Dr Berlanda, principal investigator

CONTACT

[email protected]

+39 0255031

Sponsors and collaborators

Lead sponsor

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Other

Registry information

Official study title

La Prognosi Riproduttiva Nelle Donne Che Ricercano Prole Dopo Terapia Medica o Chirurgica Per Endometriosi: Studio Multicentrico Italiano

Acronym: SURGENDO

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Feb 27, 2026
Registry last updated
Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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