Skip to main content
OpenTrials
Completed

NCT Number: NCT01853150

Repetitive Transcranial Magnetic Stimulation for Freezing of Gait

Freezing of gait (FOG) means that patients cannot walk without any known causes, other than parkinsonism, which is very disabling symptom. Patients descirbe their feeling of the feet suddenly being glued to the floor. Transcranial magnetic stiumation is a noninvasive procedure using electromagnetic induction to stimulate brain. Transcranial magnetic stiumation (rTMS) can selectively change brain activity to enhance desired effects. The aim of this study is to the therapeutic effect of rTMS for the FOG.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Movement Disorders Nervous System Diseases

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dongtan Sacred Heart Hospital

Hwaseong-si, Gyeonggi-do, 445-170, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Parkinson's disease or Primary progressive freezing of gait
  • age 18 and older
  • Freezing of gait

Exclusion criteria

  • pregnant or any, other medical, surgical, neurological or psychiatric conditions
  • other restrictions which prevent you from undergoing TMS recording, such as; surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), and/ or heart/cardiac lines
  • any past or current history of seizure disorder or epilepsy
  • unable to give informed consent

Treatment and study plan

rTMS Motor cortex

Device

rTMS Supplementary motor area

Device

Primary outcomes

  1. The number of steps

    Time frame: 2 days

    The number of steps during the stand-walk-sit (SWS) test

Secondary outcomes

  1. The completion time during the SWS test

    Time frame: 2 days

  2. Freezing episodes of gait trajectory

    Time frame: 2 days

  3. Patient and Clinical Global Impression Scale

    Time frame: 2 days

Sponsors and collaborators

Lead sponsor

Dongtan Sacred Heart Hospital

Other

Registry information

Important dates

Study start
2013
Primary completion
2018
Study completion
2018
First posted
May 14, 2013
Registry last updated
Jul 24, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.