Renal Recovery After PEEP Weaning in ARDS (RE2SDRA)

The purpose of the study is to investigate renal recovery in ARDS after PEEP weaning. The primary outcome was the variation of the hourly urine output (HUO), 48 h after PEEP weaning. Secondary outcomes were the need for RRT and mortality. Two groups were defined depending wether hourly urine output was greater or lower than 0.35 mL/kg/h.

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Key information

Conditions

ARDS (Acute Respiratory Distress Syndrome) AKI - Acute Kidney Injury Acute Kidney Injury Acute Lung Injury Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Lung Diseases Lung Injury Male Urogenital Diseases Renal Insufficiency Respiratory Tract Diseases Urogenital Diseases Urologic Diseases

Age range

15 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chu Brest

Brest, 29200, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

intubated for more than 48 hours, exposed to a PEEP≥ 8 cmH20

Exclusion criteria

chronic end-stage renal disease on admission
refusal to participate
non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity
under legal protection.

Treatment and study plan

Primary outcomes

Variation of the hourly urine output on day 2 after PEEP weaning

Time frame: From enrollement to day 2 after PEEP weaning

Variation of the hourly urine output on day 2 after PEEP weaning

Sponsors and collaborators

Lead sponsor

University Hospital, Brest

Other

Registry information

Official study title

Renal Recovery After PEEP Weaning in ARDS

Acronym: RE2SDRA

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Jan 1, 2025
Registry last updated: Jan 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed