Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT06360536

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women

The purpose of this study is to collect preliminary data on the feasibility, acceptability, and potential effects of a novel, remotely delivered resistance training program.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

About this study

This trial will enroll Black women with elevated cardiometabolic risk (e.g., overweight or obesity, pre- or established diabetes, and elevated or high blood pressure) in early-to-middle adulthood (n=36; age=30-64 years) with insufficient resistance training (RT) participation. This 4-month single group pilot trial evaluates the feasibility, acceptability, and potential effects of a novel, remotely-delivered resistance training (RT) intervention. All participants will engage in RT during this trial and the web-based platform is the primary modality through which the remote RT intervention is delivered. Assessments are conducted at baseline and follow-up (month 4). Aim 1 will examine the feasibility and acceptability of the remotely delivered RT program. Aim 2 will examine the potential effects on RT behaviors. Aim 3 will examine the potential effects on clinical and patient-reported outcomes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Self-identifies as Black or African American
  • Female
  • Age 30-64 years
  • Insufficient resistance training engagement (<2 sessions/week in the past 6 months)

AND

  • Self-reported or documented diagnosis of at least one of the following conditions: Overweight, obesity, prediabetes, type 2 diabetes, elevated blood pressure, hypertension, or taking medications for any of these conditions
  • Has an internet- connected device (i.e., computer, smartphone) and is willing to use it for intervention delivery
  • If indicated during screening, willing to obtain medical clearance for exercise from their healthcare provider prior to enrollment
  • Residing within a 50-mile radius of the University

Exclusion criteria

  • Uncontrolled hypertension (blood pressure >160/100 mm Hg)
  • Weighing ≥ 450 lbs (upper limit for body composition assessment)
  • Conditions or limitations that affect physical activity participation and/or the ability to --perform assessments
  • Has a medical or physical condition that make moderate intensity physical activity (like a brisk walk) difficult or unsafe
  • Unwilling to obtain medical clearance (if indicated by prescreening)
  • Women who are pregnant or trying to become pregnant in the next 6 months
  • Planning to relocate out of the area in the next 6 months
  • Participating in another exercise and/or randomized research project
  • Unwilling or unable to do any of the following: give informed consent; read/understand English; perform resistance training in their home, record and upload virtual exercise assessment sessions, and other protocol specific requirements

Treatment and study plan

Resistance training

Behavioral

A home-based resistance training condition that is delivered through a web-based platform.

Other names: RT

Primary outcomes

  1. Feasibility of recruitment

    Time frame: Baseline

    The number of participants enrolled in the trial

  2. Feasibility of retention

    Time frame: Month 4

    The proportion of participants who complete the study out of those who enrolled in the study

  3. Intervention adherence

    Time frame: Month 4

    The number of participants adhering to the intervention

Secondary outcomes

  1. Change in resistance training behaviors

    Time frame: Baseline and Month 4

    The number of days of resistance training completed

  2. Change in blood pressure

    Time frame: Baseline, Month 4

    Systolic and diastolic blood pressure measured by an automated device

  3. Change in HbA1C

    Time frame: Baseline, Month 4

    HbA1C measured by a point-of-care device

  4. Change in body composition

    Time frame: Baseline, Month 4

    Percent body fat measured by dual-energy x-ray absorptiometry

  5. Change in handgrip strength

    Time frame: Baseline, Month 4

    The highest value of 3 maximal attempts on each hand

  6. Change in the number of chair stands

    Time frame: Baseline, Month 4

    The number of chair stands completed in 30 seconds

Sponsors and collaborators

Lead sponsor

University of Alabama at Birmingham

Other

Collaborators

  • National Institute on Minority Health and Health Disparities (NIMHD)

Registry information

Official study title

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women: A Pilot Trial

Acronym: OVERCOME-IT

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Apr 11, 2024
Registry last updated
May 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.