University of Illinois Urbana-Champaign
Urbana, Illinois, 61801, United States
Location status: Recruiting
Location contact
Naiman Khan, PhD/RD
CONTACT
NCT Number: NCT06450977
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves thinking ability and memory compared to a healthy control diet in persons with Multiple Sclerosis (MS). The main question it aims to answer is:
Does the MIND diet improve cognitive performance relative to a control diet in persons with MS?
Participants will:
Consume one meal that follows the MIND diet or a control meal every day for 3 months, complete online surveys and cognitive testing before and after, and keep a record of the food they eat during the study.
Interested in participating?
Request Info18 year–64 year
All sexes
Interventional
Not applicable
Urbana, Illinois, 61801, United States
Location status: Recruiting
Naiman Khan, PhD/RD
CONTACT
The purpose of this study is to understand how a healthy diet is related to thinking ability and memory in people with multiple sclerosis (MS). This study is fully remote consisting of meals being delivered to participant homes using Daily Harvest meal delivery service. Participants will be asked to consume a microwaveable study meal or prepackaged smoothie every day for 12 weeks. The study meals and smoothies will follow either a dietary pattern thought to improve brain health (Mediterranean-DASH Intervention for Neurodegenerative Delay; MIND), or a control diet, and will include foods commonly found in grocery stores. Participants will not know which diet they are assigned to (active or control). Participants will also be asked to follow simple dietary guidance on a healthy diet in addition to the meals provided. Participants will complete a series of online forms or surveys. Additionally, participants will complete an online cognitive battery from Cambridge Neuropsychological Test Automated Battery (CANTAB) at the beginning and end of the study.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Daily meals designed to increase adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) dietary pattern.
Daily meals designed to increase fruit, vegetable, and whole grain intake consistent with a healthy American diet.
Time frame: 12 weeks (Baseline vs. Follow Up)
Rapid Visual Information Processing Task from CANTAB online battery
Time frame: 12 weeks (Baseline vs. Follow Up)
Match to Sample Visual Search from CANTAB online battery
Time frame: 12 weeks (Baseline vs. Follow Up)
Digit Span from CANTAB online battery
Time frame: 12 weeks (Baseline vs. Follow Up)
Paired Associates Learning Task from CANTAB online battery
Time frame: 12 weeks (Baseline vs. Follow Up)
Spatial Working Memory from CANTAB online battery
Time frame: 12 weeks (Baseline vs. Follow Up)
MIND dietary pattern scores calculated from diet records/surveys. Validated score to determine how someone adheres to the dietary pattern, scale of 0 to 14 with a higher score indicating greater adherence to the pattern.
Time frame: Throughout the recruitment process
Measure the number of participants contacted and interested in participating in the study
Time frame: Throughout the recruitment process.
Measure the number of participants that refused to participate in the intervention. Data on refusal factors will be collected through emails and calls and summarized.
Time frame: Throughout the intervention (weeks 1-12)
Retention will be described as the proportion of enrolled participants who complete the intervention
Time frame: Throughout the intervention (weeks 1-12)
Attrition is the proportion of the participants who did not complete the intervention.
Time frame: Throughout the intervention (weeks 1-12)
Adherence rates are the proportion of intervention meals and guidelines the participants followed. These will be tracked through tracking surveys throughout the intervention.
Time frame: Throughout the intervention (weeks 1-12)
Participants will report feedback on the intervention through video chats. Descriptives of participant experience and burden of intervention will be reported
Contact information is provided by the study sponsor or research team.
University of Illinois at Urbana-Champaign
Other
Acronym: REMIND
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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