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NCT Number: NCT07351916

Remission in Adults With Mild-to-moderate Asthma in Thailand

The goal of this observational study is to determine the prevalence of remission among adults with mild-to-moderate asthma, as well as the factors associated with remission in Thailand.

The main question the study aims to answer is:

What is the prevalence of remission among adults with severe asthma in Thailand? Participants will complete a questionnaire on asthma symptoms and undergo pulmonary function testing and a blood test once.

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Key information

Conditions

Asthma Asthma Control Level Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Mild-to-moderate Asthma Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Narongkorn Saiphoklang, Pathum Thani, Changwat Pathum Thani, Thailand

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About this study

This study is a cross-sectional study. Thai patients aged 18 years or older with mild-to-moderate asthma are included in the study. Participants will complete two questionnaires about asthma control: the Global Initiative for Asthma (GINA) and the Asthma Control Test (ACT), and will perform spirometry, a fractional exhaled nitric oxide (FeNO) test, and blood eosinophil counts (BEC).

GINA and ACT are questionnaires used to assess the level of asthma control.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • mild-to-moderate asthma
  • age 18 years or older

Exclusion criteria

  • inability to perform spirometry or fractional exhaled nitric oxide (FeNO) test

Treatment and study plan

Global Initiative for Asthma (GINA) and Asthma Control Test (ACT) questionnaires

Other

GINA and ACT are questionnaires used to assess the level of asthma control.

Spirometry

Other

Spirometry is a tool used to assess pulmonary function.

Fractional exhaled nitric oxide (FeNO) test

Other

FeNO is a tool used to assess eosinophilic airway inflammation and asthma remission.

Blood eosinophil count (BEC)

Other

BEC is a tool used to assess eosinophilic inflammation and asthma remission.

Primary outcomes

  1. Prevalence rate of mild-to-moderate asthma remission

    Time frame: An average of 1 year

    Prevalence rate of mild-to-moderate asthma remission (%)

Secondary outcomes

  1. Asthma control in patients with mild-to-moderate asthma

    Time frame: At baseline and at 12 months

    Rate of patients with well-controlled asthma. Well-controlled asthma is defined as an Asthma Control Test (ACT) score of 20 or higher.

  2. Airway obstruction in patients with mild-to-moderate asthma

    Time frame: At baseline and at 12 months

    Airway obstruction is assessed using FEV1/FVC ratio on spirometry.

  3. Severity of aiway obstruction in patients with mild-to-moderate asthma

    Time frame: At baseline and at 12 months

    The severity of aiway obstruction is assessed using FEV1 % predicted on spirometry.

  4. Eosinophil airway inflammation in patients with mild-to-moderate asthma

    Time frame: At baseline and at 12 months

    Eosinophil airway inflammation is assessed using blood eosinophil count (cells/µL).

  5. Type 2 airway inflammation in patients with mild-to-moderate asthma

    Time frame: At baseline and at 12 months

    Type 2 airway inflammation is assessed using fractional exhaled nitric oxide (FeNO, ppb).

Study contacts

Contact information is provided by the study sponsor or research team.

Narongkorn Saiphoklang, MD

CONTACT

[email protected]

+6629269794

Sirashat Hanvivattanakul, MD

CONTACT

[email protected]

+6629269701

Sponsors and collaborators

Lead sponsor

Thammasat University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 20, 2026
Registry last updated
Apr 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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