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NCT Number: NCT07555262

Reminder Strategies to Improve Meal-Logging Adherence

This study is a single-center micro-randomized trial, aiming to examine the effects of two theory-driven reminder strategies on adherence to repeated, image-based meal logging in adults age 45 and older. Three times daily, participants are automatically randomized to receive one of three reminder messages prior to each habitual mealtime. The main research questions the trial aims to answer are:

* Do loss-framed reminders (emphasizing loss of a daily financial reward for not logging) increase meal logging adherence in the two hours following a reminder, compared to a neutral reminder? * Do logging consistency reminders (providing feedback on recent logging streaks) increase meal logging adherence in the two hours following a reminder, compared to a neutral reminder? * Do the effects of loss-framed and logging consistency reminders differ from each other?

Primary aim: To estimate the proximal effect of each reminder type on whether a participant logs a meal within two hours of receiving a reminder.

Secondary aim: To examine whether within-person physiological patterns (e.g., heart rate variation) moderate response to reminders, with the goal of identifying physiological markers of receptivity to behavioral prompts.

The trial aims to enroll 200 adults aged 45 and older. Participants attend a baseline visit for onboarding, consent, and device setup, followed by a 28 day remote intervention period during which they should photograph their meals three times daily (breakfast, lunch, dinner) and wear a smartwatch and smart ring continuously. Prior to each mealtime, they receive an automatically randomized reminder message. Participants earn a daily financial reward contingent on completing meal logging for that day.

Note: This trial was registered retrospectively as enrollment began prior to registration. However, registration was completed before data collection was finished and before any data analysis was conducted.

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Key information

Age range

45 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

HOCH Health and School of Medicine, University of St. Gallen

Sankt Gallen, Canton of St. Gallen, 9000, Switzerland

Location status: Recruiting

Location contact

Mia Jovanova, Dr.

CONTACT

[email protected]

+41 44 632 05 41

Mia Jovanova, Dr.

PRINCIPAL_INVESTIGATOR

Michael Brändle, Prof.Dr.med

PRINCIPAL_INVESTIGATOR

Tobias Kowatsch, Prof.Dr.

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Citizens or residents of Switzerland who are German-speaking (main place of living or employment in Switzerland).
  • Age ≥45 years.
  • BMI ≥25 kg/m² (overweight or obese).
  • Regular access to a smartphone (iOS or Android) with a data plan.
  • Able to use smartphone applications.
  • Able to walk independently.

Exclusion criteria

  • History of stroke, heart disease, renal failure, cancer, or diabetes (type 1 or type 2).
  • Past vascular bypass surgery or angioplasty.
  • Current or planned use of glucose-lowering medications during the upcoming 4 weeks (e.g., GLP-1 receptor agonists, metformin).
  • Pregnant or breastfeeding.
  • Relevant skin conditions at wearable placement sites (e.g., upper arm).
  • BMI <25 kg/m² confirmed at enrollment.
  • FPG ≥7.0 mmol/L and/or HbA1c ≥6.5% (newly identified type 2 diabetes); Individuals who meet type-2 diabetes criteria at enrollment, based on Swiss/ADA diagnostic criteria will be informed of blood test results and referred to a GP. These individuals will be deemed ineligible and excluded from the study.

Treatment and study plan

Loss-Framed Reminder

Behavioral

Push notification emphasizing loss of daily financial reward for not logging the upcoming meal.

Logging Consistency Reminder

Behavioral

Push notification providing feedback on recent meal logging streak.

Neutral Reminder

Behavioral

Push notification reminding participants to log a meal.

Primary outcomes

  1. Meal Logging Adherence

    Time frame: Within 2 hours of each decision point, assessed over 28 days

    Proportion of decision points at which a participant logs a meal within 2 hours of receiving a reminder, compared across reminder types (loss-framed, logging consistency, and neutral control).

Secondary outcomes

  1. Moderators of Reminder Responsiveness

    Time frame: Assessed over 28 days

    Meal logging adherence (binary, within 2 hours of a decision point) examined as a function of participant-level moderators including physiological (e.g., heart rate variability), demographic (e.g., age, sex), and behavioral characteristics, to identify moderators of differential responsiveness to reminder types.

Study contacts

Contact information is provided by the study sponsor or research team.

Mia Jovanova, Dr.

CONTACT

[email protected]

+41 44 632 05 41

Sponsors and collaborators

Lead sponsor

University of St.Gallen

Other

Registry information

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Apr 29, 2026
Registry last updated
May 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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