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NCT Number: NCT06136169

Reminder-cue Scanning Training for Homonymous Visual Field Loss

This study will evaluate a new approach to training people with visual field loss to scan when driving

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Homonymous Hemianopia Blindness Eye Diseases Hemianopsia Homonymous Quadrantanopia Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Sensation Disorders Signs and Symptoms Vision Disorders

Age range

16 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Schepens Eye Research Institute of Mass Eye and Ear

Boston, Massachusetts, 02114, United States

About this study

Homonymous visual field loss is the loss of vision on the same side in both eyes. The most common types are hemianopia (the loss of one half of the field of vision) and quadrantanopia (the loss of one quarter of the field of vision). Hemianopia and quadrantanopia may cause difficulties in seeing objects on the side of the field loss. People with these types of field loss can compensate by scanning (looking) toward the side of the field loss. However, sometimes they might not scan sufficiently well resulting in delayed responses to hazards when driving. The purpose of this research study is to evaluate a new approach, "reminder-cue scanning training", to training people with homonymous visual field loss to scan when driving.

Participants will receive reminder-cue scanning training in the driving simulator.Typically there will be three training sessions within about a 2-week period. In addition, participants will complete an evaluation in the driving simulator before and after the training.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Homonymous hemianopia or homonymous quadrantanopia for at least 3 months
  • Binocular visual acuity of at least 20/40
  • Prior or current driving experience
  • Able to attend multiple study visits
  • Able to communicate in English sufficiently to understand the study procedures

Exclusion criteria

  • Physical or general health problems that could impair the ability to operate the controls of the driving simulator or participate in the training

Treatment and study plan

Reminder-cue scanning training

Behavioral

Auditory reminders to scan when scanning to the side of the field loss is inadequate

Primary outcomes

  1. Rate of Early Large Head Scans to the Side of the Field Loss

    Time frame: Pre-training, post-training (1 week)

    Percentage of intersections at which an early large head scan was made to the side of the field loss

  2. Detection Rate for Hazards on the Side of the Field Loss

    Time frame: Pre-training, Post-training (1 week)

    Percentage of hazards detected out of the total number of hazards on the side of the field loss

Secondary outcomes

  1. Number of Head Scans to the Side of the Field Loss

    Time frame: Pre-training, Post-training (1 week)

    Number of head scans per intersection to the side of the field loss. A validated algorithm was used to detect head scans, defined as lateral rotations of the head away from the straight ahead position toward either the left or the right, which exceeded a predefined threshold based on the participant's distance to the intersection: ≥ 4° (100 to 50 m to intersection), ≥ 6° (50 to 20m), ≥ 10° (20 to 0m).

    Savage SW, Zhang L, Swan G, Bowers AR (2020) The effects of age on the contributions of head and eye movements to scanning behavior at intersections. Transp Res Part F Traffic Psychol Behav. 73:128-142.

    Swan G, Goldstein RB, Savage SW, Zhang L, Ahmadi A, Bowers AR (2021) Automatic processing of gaze movements to quantify gaze scanning behaviors in a driving simulator. Behav Res Methods. 53(2): 487-506

  2. Magnitude of Head Scans to the Side of the Field Loss

    Time frame: Pre-training, Post-training (1 week)

    Mean magnitude (in degrees) of head scans to the side of the field loss. A validated algorithm was used to detect head scans, defined as lateral rotations of the head away from the straight ahead position toward either the left or the right, which exceeded a predefined threshold based on the participant's distance to the intersection: ≥ 4° (100 to 50 m to intersection), ≥ 6° (50 to 20m), ≥ 10° (20 to 0m). The magnitude is the lateral angular extent of the scan measured from the straight-ahead position to the furthest lateral position to the left or right.

    Savage SW, Zhang L, Swan G, Bowers AR (2020) The effects of age on the contributions of head and eye movements to scanning behavior at intersections. Transp Res Part F Traffic Psychol Behav. 73:128-142.

    Swan G, Goldstein RB, Savage SW, Zhang L, Ahmadi A, Bowers AR (2021) Automatic processing of gaze movements to quantify gaze scanning behaviors in a driving simulator. Behav Res Methods. 53(2): 487-506

  3. Response Times to Hazards on the Side of the Field Loss

    Time frame: Pre-training, Post-training (1 week)

    Mean time (in seconds) between the hazard appearing and the horn-press response

Sponsors and collaborators

Lead sponsor

Massachusetts Eye and Ear Infirmary

Other

Collaborators

  • National Eye Institute (NEI)

Registry information

Official study title

Reminder-cue Scanning Training for People With Homonymous Visual Field Loss

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Nov 18, 2023
Registry last updated
Jul 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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