Skip to main content
OpenTrials
Completed

NCT Number: NCT02001298

Remifentanil and Nitroprusside for Controlled Hypotension

The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hypotension, Controlled Cardiovascular Diseases Hypotension Vascular Diseases

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Jeju National University Hospital

Jeju City, Jeju Special Self-Governing Province, 690-767, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who underwent endoscopic sinus surgery

Exclusion criteria

  • patient who took any drug to influence this study
  • patient with cardiovascular disease, renal disease or liver disease

Treatment and study plan

Remifentanil

Drug

nitroprusside

Drug

Primary outcomes

  1. Cardiac index

    Time frame: Cardiac index was continuously measured during controlled hypotension, an average of 90 min

    Cardiac index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of cardiac index during controlled hypotension was compared with baseline value.

Secondary outcomes

  1. Total peripheral resistance index

    Time frame: Total peripheral resistance index was continuously measured during controlled hypotension, an average of 90 min

    Total peripheral resistance index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of total peripheral resistance index during controlled hypotension was compared with baseline value.

Other outcomes

  1. Stroke volume index

    Time frame: Stroke volume index was continuously measured during controlled hypotension, an average of 90 min

    Stroke volume index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of stroke volume index during controlled hypotension was compared with baseline value.

Sponsors and collaborators

Lead sponsor

Jeju National University School of Medicine

Other

Registry information

Official study title

The Comparison of the Cardiovascular Effects of Remifentanil and Nitroprusside for Controlled Hypotension

Important dates

Study start
2012
Primary completion
2013
First posted
Dec 4, 2013
Registry last updated
Dec 4, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.