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Completed

NCT Number: NCT05886842

Reliability (Test-retest) of 30 Seconds Sit-to-stand and Timed Up and Go in Adults With Long Covid

The goal of this study is to test the reliability (with a test-retest process) of 30 seconds Sit to Stand and Timed Up and Go in an adult population with long-covid, hospitalised in a rehabilitation center.

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Key information

About this study

Since December 2019, Covid-19 has affected millions of people worldwide, leaving many of them with symptoms such as fatigue, (muscle) weakness and dyspnoea, even months after their infection (long covid). Rehabilitation centers were established to aid this new group of patients. This study's aim is to test the reliability of 2 outcome measures for patients with long covid. 30 seconds Sit-To-Stand and Timed Up And Go tests are not specific to a disease but they evaluate functionality, mobility and endurance. They are easy to perform in a clinical setting as they do not require specific equipment. The reliability of the above tests has yet to be established in people with long covid.

A sample size of 19 people will be used. A difference in reliability of 0.9 and 0.7 at 80% power and a 5% level of significance using two ratings was set. Based on two testing sessions, an x value of 0.05, and a power of 0.80, a minimal sample size of 19 patients was identified (Karagiannis et al., 2020).

19 patients with long covid from the rehabilitation center will take both tests in a single day and 3 days later they will take the tests again with no physical therapy intervention in between the measurements.

For the statistical analysis, ICC (Intra-class correlation coefficients), SEM (standard error of measurement) and Bland-Altman plot will be used. These tests evaluate test-retest reliability, through the identification of the agreement of patient's scores between the 2 measurements and they evaluate the measurement precision (Savva et al, 2014).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults who were infected with COVID-19 virus in the last 6 months and were diagnosed with long-covid
  • Patients must be willing to give written consent for participation in the study
  • Negative rapid test for COVID-19

Exclusion criteria

  • People under 18 years of age
  • Significant cognitive and psychiatric impairments (inability to follow simple commands or give consent)
  • Refuse to give consent

Treatment and study plan

Test-retest

Other

Test-retest

Other names: Reliability

Primary outcomes

  1. Reliability of 30 seconds Sit to stand

    Time frame: Two occasions within approximately three days to establish intra rater reliability

    Test-retest that assess the reliability of 30 seconds Sit to Stand

  2. Reliability of Timed Up and Go

    Time frame: Two occasions within approximately three days to establish intra rater reliability

    Test-retest that assess the reliability of Timed Up and Go

Sponsors and collaborators

Lead sponsor

European University Cyprus

Other

Collaborators

  • Eden Resort Wellness Rehabilitation Center

Registry information

Official study title

Reliability of 30 Seconds Sit-to-stand and Timed Up and Go in Adults With Long Covid

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Jun 2, 2023
Registry last updated
Aug 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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