Enrolling by Invitation

NCT Number: NCT06105866

Relationship of Preoperative Fasting With Tricuspid Annular Plane Systolic Excursion

The aim of our study is to try to establish a relationship between preoperative fasting-related volume changes and tricuspid annular plane systolic excursion (TAPSE), and to determine whether there are changes in right ventricular functions due to preoperative fasting.

Enrolling by Invitation

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Key information

Conditions

The Relationship Between TAPSE Value and Volume

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sevil Gulasti

Aydin, Zafer, 09010, Turkey (Türkiye)

About this study

TAPSE (Tricuspid Annular Plane Systolic Excursion) is a parameter that easily measures apex-base shortening and provides specific information about global right ventricular (RV) function. It is less dependent on optimal image quality and serves as an easily measurable criterion compared to other RV function measurements. In this study, one day before the operation, transthoracic echocardiography (TTE) will be conducted on fasting patients, and if the preoperative fasting duration is appropriate on the day of the surgery, TTE measurements will be repeated and recorded. The study aims to evaluate the relationship between TAPSE and volume and determine whether there are any changes in right ventricular functions due to preoperative fasting.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ASA 1-2-3
The patient must be between 18 and 75 years old.
Perioperative hydration has not been administered.
Preoperative sedatives have not been given.
There should be no known heart disease.

Exclusion criteria

The patient being pregnant
Post-cardiac surgery
Severe pulmonary hypertension
Severe valve disease
Hypertrophic or dilated cardiomyopathy
Presence of acute myocardial infarction
Non-sinus rhythm

Treatment and study plan

Tricuspid Annular Plane Systolic Excursion

Diagnostic Test

Transthoracic echocardiography will be performed on patients during hospitalization and preoperatively to investigate the relationship between preoperative fasting and right ventricular functions. This will be examined by looking at TAPSE

Primary outcomes

The TAPSE value is related to volume

Time frame: Patients who apply to our hospital for surgery within 6 months will be included in our study. Preoperative TAPSE measurements will be taken from the patients twice, first during admission and immediately before the operation

We will measure FAC, S' velocity, TAPSE, and Myocardial Performance Index (MPI) derived from TDI to evaluate Right Ventricular (RV) systolic functions. To assess the RV diastolic function, we will measure Tricuspid E and A wave velocities, E/A ratio, and E' velocity. TAPSE will be calculated by placing an M-mode cursor along the Tricuspid Annulus and measuring the longitudinal excursion during peak systole

Sponsors and collaborators

Lead sponsor

Aydin Adnan Menderes University

Other

Registry information

Official study title

Relationship of Preoperative Fasting With Tricuspid Annular Plane Systolic Excursion (TAPSE)

Acronym: (TAPSE)

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Oct 30, 2023
Registry last updated: Dec 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.