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Completed

NCT Number: NCT04583631

Relationship of Endoplasmic Reticulum Stress and Adenoid Diseases

Adenoid tissue is a significant organ for the performing of immune systems in children. The Endoplasmic Reticulum (ER), is an organelle needed for the care of a stable function of cells. The purpose of the study was to explore the correlation among ER stress and adenoid tissue disorders and to explain the structure of diseases related to the immune system.

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Key information

Conditions

Adenoiditis Acute Infective

Age range

3 year–9 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Selcuk University

Konya, Selcuklu, 42100, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with the clinical diagnosis of chronic adenoiditis and adenoid hypertrophy.

Exclusion criteria

  • Systemic diseases
  • Other otolaryngological

Treatment and study plan

Adenoidectomy surgery

Procedure

All patients underwent adenoidectomy under general anesthesia by routine curettage method and adenoid tissues were put in formaldehyde and sent to the genetics department for the exploration of ER stress and apoptosis markers.

Primary outcomes

  1. Correlation of ER stress and apoptosis with chronic adenoiditis and adenoid hypertrophy

    Time frame: 2018-2019 (1 year)

    Our primary outcome was to evaluate providing that ER stress and apoptosis reaction performing in chronic adenoiditis and adenoid hypertropy, which is related with the immune system of children.

Sponsors and collaborators

Lead sponsor

Selcuk University

Other

Registry information

Official study title

Relationship Between Apoptosis and er Stress in Chronic Adenoiditis and Adenoid Hypertrophy

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Oct 12, 2020
Registry last updated
Sep 27, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.